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NCT05248464
Distress Related to the Feeling of Loss of Dignity in Patients With Rheumatic Diseases
trial testing The Patient Dignity Inventory instrument (PDI) in Rheumatic Diseases in 309 participants. Status unknown.
1 March 2023
Quick facts
| Lead sponsor | National Institute of Medical Sciences and Nutrition, Salvador Zubiran |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 309 |
| Start date | 1 March 2022 |
| Primary completion | 1 March 2023 |
| Estimated completion | 1 March 2023 |
| Sites | 1 location across Mexico |
Drugs / interventions tested
- The Patient Dignity Inventory instrument (PDI)
- WHOQOL-BREF (quality of life) instrument
Conditions studied
- Rheumatic Diseases — all drugs for Rheumatic Diseases →
- Dignity — all drugs for Dignity →
- Quality of Life — all drugs for Quality of Life →
- Distress, Emotional — all drugs for Distress, Emotional →
Sponsor
National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Who can join
Adults 18 to 99, any sex, with Rheumatic Diseases or Dignity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Rheumatic diseases (RD) are an important group of different clinical entities and specific diseases that affect a significant proportion of the world population. In Mexico, the RD have a relevant representation in the adult population. Dignity is a construct characterized by the representation of the self, of the self from others' point of view, and of the interaction of the individual with the environment and social context. Living with a chronic illness can threaten experiences of dignity for the sick person and their families. Various studies have demonstrated the direct impact of the disease on dignity in terms of physical and psychological symptoms and loss of function. Some efforts have been made to operationalize the concept of perceived dignity in the context of chronic diseases The perceived dignity of patients and the distress related to the feeling of loss of dignity (DRFLD) are outcomes that the patient can report and that the doctors can evaluate to be incorporated into the considerations of comprehensive care. Both outcomes are closely related, perceived dignity refers to a complex phenomenon, while distress related to the feeling of loss of dignity identifies those patients with a perceived dignity compromise of such magnitude that it generates anguish.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Perceived dignity is an unrecognized source of emotional distress in patients with rheumatic diseases: Results from the validation of the Mexican version of the Patient Dignity Inventory.
Pascual-Ramos V, Contreras-Yáñez I, Cuevas-Montoya M, Guaracha-Basáñez GA, et al · · 2023 · cited 4× · PMID 37540659 · DOI 10.1371/journal.pone.0289315 -
The impact of underlying RMD diagnosis on dignity landscape in patients with systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosis.
Pascual-Ramos V, Contreras-Yáñez I, Cuevas-Montoya M, Guaracha-Basáñez G, et al · · 2025 · PMID 40696675 · DOI 10.1097/md.0000000000043303
Verify or expand the search:
- PubMed search for NCT05248464
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other National Institute of Medical Sciences and Nutrition, Salvador Zubiran trials
Trials by the same sponsor.
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- NCT06386380 — Adversity and Its Association With the Development and Expression of Rheumatic Diseases · not yet recruiting
- NCT06233760 — Prevalence of Abuse Among Patients With Rheumatic Diseases · unknown
- NCT05676359 — Knowledge of Living Will in Patients With Rheumatic Diseases · unknown
- NCT04775563 — COVID-19 Vaccine Hesitancy Among Rheumatic Diseases Patients · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05248464 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Medical Sciences and Nutrition, Salvador Zubiran
- Last refreshed: 6 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05248464.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing