NCT05211505 is a Phase 4 clinical trial of WO 2707 in Vaginal Atrophy, sponsored by Dr. August Wolff GmbH & Co. KG Arzneimittel.

Who is sponsoring NCT05211505?

NCT05211505 is sponsored by Dr. August Wolff GmbH & Co. KG Arzneimittel.

What drugs are being tested in NCT05211505?

Interventions in NCT05211505: WO 2707.

What condition does NCT05211505 study?

NCT05211505 studies Vaginal Atrophy.

Is NCT05211505 still recruiting?

NCT05211505 is currently completed. Last updated 27 April 2022.

Last reviewed 2022-04-27 · How we verify

NCT05211505

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Investigation of Efficacy and Tolerability of WO 2707, a MoistCream Cremolum, in Postmenopausal Women Suffering From Symptoms of Vaginal Dryness

Completed Phase 4 Last updated 27 April 2022

What this trial tests

Phase 4 trial testing WO 2707 in Vaginal Atrophy in 79 participants. Completed in 24 March 2022.

Timeline

31 January 2022

Primary endpoint
24 March 2022

24 March 2022

Quick facts

Lead sponsor	Dr. August Wolff GmbH & Co. KG Arzneimittel
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	79
Start date	31 January 2022
Primary completion	24 March 2022
Estimated completion	24 March 2022
Sites	1 location across Germany

Drugs / interventions tested

WO 2707

Conditions studied

Vaginal Atrophy — all drugs for Vaginal Atrophy →

Sponsor

Dr. August Wolff GmbH & Co. KG Arzneimittel

Who can join

18 and older, female only, with Vaginal Atrophy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of the clinical investigation is to evaluate the efficacy and tolerability of WO 2707, a MoistCream Cremolum, with respect to the application in postmenopausal women with symptoms of vaginal dryness.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

An effective non-hormonal option with high tolerability for mild to moderate symptoms of vaginal dryness associated with menopause.
Eichler S, Panz M, Harder A, Masur C, et al · · 2024 · cited 2× · PMID 38583316 · DOI 10.1016/j.maturitas.2024.107978
Psychometric evaluation of the German Day-to-Day Impact of Vaginal Aging questionnaire using data from two intervention studies.
Gabes M, Donhauser T, Harder A, Masur C, et al · · 2023 · cited 1× · PMID 36787527 · DOI 10.1097/gme.0000000000002161

Verify or expand the search:

Other recruiting trials for Vaginal Atrophy

Currently open trials in the same condition.

NCT05457972 — Postpartum Vaginal Estrogen for Breastfeeding Patients · Phase 4 · recruiting
NCT06028009 — PRP Injections for Genitourinary Syndrome of Menopause · NA · active not recruiting
NCT07024667 — Clinical and Molecular Study to Evaluate the Effect of the Pixel CO2 Laser (FemiLiftTM) for the Treatment of Vulvo-Vagin · NA · recruiting
NCT05335317 — Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser · NA · recruiting
NCT04807894 — Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo · Phase 4 · recruiting

Other Dr. August Wolff GmbH & Co. KG Arzneimittel trials

Trials by the same sponsor.

NCT06244615 — Clinical Trial of a Mouth and Throat Rinse for the Treatment of Acute Sore Throat · NA · completed
NCT05863104 — Assessment of Safety, Tolerability, Systemic Exposure and Efficacy of GPB Cream in Adolescents With Severe Primary Hyper · Phase 2 · completed
NCT04222647 — Investigation of Efficacy and Tolerability of a Lactic Acid Containing Vaginal Suppository in Post-menopausal Women With · Phase 2 · completed
NCT03658616 — Assessment of Efficacy and Safety of Topical Administration of 1% Glycopyrronium Bromide (GPB) in Patients With Primary · Phase 3 · completed
NCT03630107 — In-Use Test of a Cosmetic Product in Subjects With Chronically Itchy Scalp · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05211505 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Dr. August Wolff GmbH & Co. KG Arzneimittel
Last refreshed: 27 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05211505.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing