Last reviewed · How we verify
NCT07024667: VVA PAP POPQ
Clinical and Molecular Study to Evaluate the Effect of the Pixel CO2 Laser (FemiLiftTM) for the Treatment of Vulvo-Vaginal Atrophy
NA trial testing Pixel CO2 Laser for the Treatment of Vulvo-Vaginal Atrophy (VVA) in Vulvar Atrophy in 20 participants. Currently enrolling.
31 December 2027
Quick facts
| Lead sponsor | Hillel Yaffe Medical Center |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 2 September 2022 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across Israel |
Drugs / interventions tested
- Pixel CO2 Laser for the Treatment of Vulvo-Vaginal Atrophy (VVA)
Conditions studied
- Vulvar Atrophy — all drugs for Vulvar Atrophy →
- Vaginal Atrophy — all drugs for Vaginal Atrophy →
Sponsor
Hillel Yaffe Medical Center
Who can join
Adults 45 to 75, female only, with Vulvar Atrophy or Vaginal Atrophy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Vulvo Vaginal Atrophy (VVA) refers to the changes in the vaginal and vulvar surfaces that occurs during menopause due to the progressive loss of estrogen. The low levels of circulating estrogen produce a wide variety of anatomic, physiologic, and clinical changes in the urogenital area. Clinical symptoms include vaginal dryness, irritation, soreness, dyspareunia, dysuria, and vaginal discharge. In recent years, microablative fractional CO2 laser has become available for treating vaginal atrophy. It showed a regenerative property with significant histological changes in cellular and connective tissue components. Treatment with the fractional CO2 laser resulted in restoration of the vaginal epithelium with ultrastructural findings, similar to a premenopausal state, that included thickened stratified squamous epithelium with increased collagen support, increased glycogen in epithelial cells, increased fibroblasts, increased vascularity, and presence of sub-epithelial papillae.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07024667
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Hillel Yaffe Medical Center trials
Trials by the same sponsor.
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- NCT07320339 — The Aim of the Study is to Examine the Variation in Blood Pressure Between an Optimal Measurement (According to Establis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07024667 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hillel Yaffe Medical Center
- Last refreshed: 17 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07024667.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing