NCT05207319

Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia

Completed NA Last updated 26 January 2022

What this trial tests

NA trial testing integrated Moral Reasoning Development Intervention (MRDI) in Schizophrenia in 43 participants. Completed in 31 December 2020.

Timeline

1 September 2019

Primary endpoint
31 December 2020

31 December 2020

Quick facts

Lead sponsor	I-Shou University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	43
Start date	1 September 2019
Primary completion	31 December 2020
Estimated completion	31 December 2020
Sites	1 location across Taiwan

Drugs / interventions tested

• integrated Moral Reasoning Development Intervention (MRDI)

Conditions studied

• Schizophrenia — all drugs for Schizophrenia →
• Moral Status — all drugs for Moral Status →
• Violence — all drugs for Violence →

Sponsor

I-Shou University

Who can join

Adults 20 to 65, any sex, with Schizophrenia or Moral Status. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Moral cognition is an important and multidimensional, but often overlooked, determinant of violence. Very few interventions have systematically examined the role of moral reasoning, anger management and problem-solving together in violence. A randomized controlled trial was conducted to comprehensively evaluate the sustained effects of an integrated Moral Reasoning Development Intervention (MRDI) on management of repetitive violence in schizophrenia. This study placed special emphasis on essential components related to moral reasoning and violence in patients with schizophrenia. Evaluations including measures of violence, moral reasoning, ethical valuation and judgement, decision-making, conflict management style, and personality traits, were performed at baseline, end of intervention, and 1-month follow-up after intervention. MRDI was superior to treatment-as-usual in improving moral reasoning and related variables and violence outcomes. In comparison with the treatment-as-usual group, patients in the MRDI group showed improved levels of moral reasoning whereas decreased levels of violent behaviors. The MRDI participants also experienced significantly greater improvements or changes in their ethical valuation and judgement, decision-making style and preferences, and conflict management style. Our findings provide important implications for risk assessment and violence management and prevention.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia: A Randomized Controlled Trial.
   Hsu MC, Ouyang WC. · · 2022 · cited 3× · PMID 35268258 · DOI 10.3390/jcm11051169