Who is sponsoring NCT05202821?

NCT05202821 is sponsored by Ain Shams University.

What drugs are being tested in NCT05202821?

Interventions in NCT05202821: PRG Barrier Coat, Fluoride varnish, MI paste.

What condition does NCT05202821 study?

NCT05202821 studies White Spot Lesions [Initial Caries] on Smooth Surface of Tooth.

Is NCT05202821 still recruiting?

NCT05202821 is currently status unknown. Last updated 24 January 2022.

Last reviewed 2022-01-24 · How we verify

NCT05202821

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients

Status unknown Phase 1 Last updated 24 January 2022

What this trial tests

Phase 1 trial testing PRG Barrier Coat in White Spot Lesions [Initial Caries] on Smooth Surface of Tooth in 60 participants. Status unknown.

Timeline

1 January 2021

Primary endpoint
30 March 2022

30 June 2022

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 1
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	60
Start date	1 January 2021
Primary completion	30 March 2022
Estimated completion	30 June 2022
Sites	1 location across Egypt

Drugs / interventions tested

PRG Barrier Coat — full drug profile →
Fluoride varnish
MI paste — full drug profile →

Conditions studied

White Spot Lesions [Initial Caries] on Smooth Surface of Tooth — all drugs for White Spot Lesions [Initial Caries] on Smooth Surface of Tooth →

Sponsor

Ain Shams University

Who can join

Adults 10 to 16, any sex, with White Spot Lesions [Initial Caries] on Smooth Surface of Tooth. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In-Vivo randomized clinical trial to compare between the clinical performance of fluoride varnish versus MI paste (CPP\_ACP) and the PRG- Barrier coat material concerning enamel remineralization, arrest of active early lesions, resolution of inactive incipient lesions and patient satisfaction and motivation with a 9-months follow up using a high resolution Nikon camera with Canon 700D body. Canon EF 100mm f2.8 USM Macro Lens and Nissin MF18 ring flash Canon fit for better illumination. Also, A set of retractors and A set child occlusal mirrors with A contraster for assessment of the remineralization progress of the white spot lesion.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for White Spot Lesions [Initial Caries] on Smooth Surface of Tooth

Currently open trials in the same condition.

NCT06696105 — Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions · Phase 4 · active not recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05202821 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 24 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05202821.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing