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MI paste
MI Paste delivers calcium and phosphate ions to remineralize and strengthen tooth enamel and dentin.
MI Paste delivers calcium and phosphate ions to remineralize and strengthen tooth enamel and dentin. Used for Dental caries prevention and remineralization, Tooth sensitivity management, Enamel and dentin remineralization.
At a glance
| Generic name | MI paste |
|---|---|
| Also known as | RECALDENT™, (CPP-ACP) |
| Sponsor | Ain Shams University |
| Drug class | Remineralizing agent |
| Modality | Small molecule |
| Therapeutic area | Dentistry |
| Phase | FDA-approved |
Mechanism of action
MI Paste is a topical dental cream containing calcium and phosphate in a water-based paste formulation. It works by releasing bioavailable calcium and phosphate ions that penetrate into demineralized tooth structure, promoting remineralization and hardening of enamel and dentin. This helps reverse early caries lesions and reduce tooth sensitivity.
Approved indications
- Dental caries prevention and remineralization
- Tooth sensitivity management
- Enamel and dentin demineralization
Common side effects
- Mild irritation or sensitivity
- Taste disturbance
Key clinical trials
- Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics (NA)
- Use of Two Dissolvable Therapeutics Under Removable Partial Dentures (NA)
- Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers (NA)
- Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment (NA)
- Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children (NA)
- The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching (NA)
- In-situ Evaluation of Anti-caries Technology
- Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MI paste CI brief — competitive landscape report
- MI paste updates RSS · CI watch RSS
- Ain Shams University portfolio CI