Who is sponsoring NCT05186259?

NCT05186259 is sponsored by University Ghent.

What drugs are being tested in NCT05186259?

Interventions in NCT05186259: Self-reported signs of central sensitization, Objective signs of central sensitization, Audiological outcome measures (audiometry, tinnitus analysis, uncomfortable loudness) in tinnitus patients with and without pain, Cognitive functioning, Listening effort, Self-reported psychological factors, Self-reported lifestyle factors, Self-reported measure of pain processing, Self-reported quality of life, Self-reported tinnitus severity and impact on daily life, Self-reported hyperacusis, Self-reported tinnitus characteristics, Self reported neck pain related disability.

What condition does NCT05186259 study?

NCT05186259 studies Tinnitus, Pain.

Is NCT05186259 still recruiting?

NCT05186259 is currently completed. Last updated 9 January 2024.

Last reviewed 2024-01-09 · How we verify

NCT05186259

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain

Completed NA Last updated 9 January 2024

What this trial tests

NA trial testing Self-reported signs of central sensitization in Tinnitus in 135 participants. Completed in 1 April 2022.

Timeline

21 December 2021

Primary endpoint
1 April 2022

1 April 2022

Quick facts

Lead sponsor	University Ghent
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	screening
Enrollment	135
Start date	21 December 2021
Primary completion	1 April 2022
Estimated completion	1 April 2022
Sites	1 location across Belgium

Drugs / interventions tested

Self-reported signs of central sensitization
Objective signs of central sensitization
Audiological outcome measures (audiometry, tinnitus analysis, uncomfortable loudness) in tinnitus patients with and without pain
Cognitive functioning
Listening effort
Self-reported psychological factors
Self-reported lifestyle factors
Self-reported measure of pain processing
Self-reported quality of life
Self-reported tinnitus severity and impact on daily life
Self-reported hyperacusis
Self-reported tinnitus characteristics
Self reported neck pain related disability

Conditions studied

Tinnitus — all drugs for Tinnitus →
Pain — all drugs for Pain →

Sponsor

University Ghent

Who can join

Adults 18 to 65, any sex, with Tinnitus or Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a cross-sectional investigation into modulating mechanisms in patients with chronic subjective tinnitus, which will compare 4 patient groups namely chronic tinnitus with chronic pain, chronic tinnitus without chronic pain, chronic pain without tinnitus and healthy controls.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Suffering from chronic tinnitus, chronic neck pain, or both: Does it impact the presence of signs and symptoms of central sensitization?
De Meulemeester K, Meeus M, De Pauw R, Cagnie B, et al · · 2023 · cited 12× · PMID 37616265 · DOI 10.1371/journal.pone.0290116

Verify or expand the search:

Other recruiting trials for Tinnitus

Currently open trials in the same condition.

NCT07393880 — Bimodal Electrical-Sound Stimulation and Auditory Training for Chronic Tonal Tinnitus · NA · recruiting
NCT07071480 — Noninvasive Therapy for Tinnitus · NA · recruiting
NCT07435298 — Navigated Repetitive TMS for Chronic Tinnitus · NA · recruiting
NCT07158034 — Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation · NA · recruiting
NCT07017998 — External Therapy for Tinnitus Management · NA · recruiting

Other University Ghent trials

Trials by the same sponsor.

NCT07398053 — General Practitioner & Pharmacist Support for Discontinuing Long-term Antidepressants in Clinically Stable Patients · NA · not yet recruiting
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NCT07091071 — Evaluation of the CochSyn Device in Clinical Practice · NA · completed
NCT07259408 — Co-creation of Tools for People in Detention With Suicidal Thoughts and/or Behavior · recruiting
NCT07176156 — Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05186259 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Ghent
Last refreshed: 9 January 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05186259.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing