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NCT05183386

Histological Outcome of the Use of Different Biomaterials for Fresh Socket Regeneration. A Split-mouth Design

Completed NA Last updated 11 January 2022
What this trial tests

NA trial testing dental socket regeneration in Alveolar Bone Loss in 30 participants. Completed in 1 January 2020.

Timeline
1 January 2014
Primary endpoint
1 January 2019
1 January 2020

Quick facts

Lead sponsorUniversity of Salamanca
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment30
Start date1 January 2014
Primary completion1 January 2019
Estimated completion1 January 2020

Drugs / interventions tested

Conditions studied

Sponsor

University of Salamanca

Who can join

Adults 18 to 75, any sex, with Alveolar Bone Loss. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Purpose: The aim of this study was to analyze the quality of bone regeneration in fresh sockets using four different materials and at different times points. Materials and Methods: A split-mouth clinical trial was designed to evaluate the histological and histomorphometrical characteristics of fresh sockets from 30 patients. One socket per patient will healed spontaneously (control) and, at least, one fresh socket, will be grafted with platelet-rich growth factor (PRGF), PRGF+autologous bone, autologous bone or PRGF+demineralized freeze dried bone allograft (DFDBA). The day of the implant placement, biopsies will be taken at different time points divided into three assessment groups: short duration (2-4 months), intermediate duration (5-6 months) and long duration (7-12 months). The histologic findings will be assessed to quantify the trabeculae pattern, the degree of mineralization and the quality of bone regeneration.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Alveolar Bone Loss

Currently open trials in the same condition.

Other University of Salamanca trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05183386.

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