18 and older, any sex, with Vaccination Refusal or COVID-19 Pandemic. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Changes in County-Level Covid-19 Vaccination Measured by Inverse Hyperbolic SinePrimary· During intervention (6 weeks) and after intervention (3 weeks)
County-level Covid-19 vaccination rates were analysed using publicly available data. The number of new vaccinations in each county was transformed using the inverse hyperbolic sine because the underlying vaccination count data were right-skewed and included zeros. Larger numbers are considered better in the context of the study (more people vaccinated).
Group
Value
95% CI
Control
0
0 – 0
Treatment 1: Direct
-0.023
-0.10 – 0.055
Treatment 2: Friends
-0.007
-0.081 – 0.067
Treatment 3: Gossips
-0.037
-0.11 – 0.034
Sponsor's own description
This study will distribute videos of health professionals encouraging Covid-19 vaccination to a large sample of Facebook users, and will test the most effective ways to maximize diffusion of this vaccine-related content to increase vaccination rates. The study sample will be U.S. states where vaccination rates remained low in fall 2021. The experimental design is an RCT with 4 groups, randomized at the county level: 1) a control group which receives no intervention, 2) a treatment group in which Facebook users receive ads which include videos of health professionals telling them to get vaccinated, 3) a treatment group in which Facebook users receive ads which include videos of health professionals encouraging them to help their friends to get vaccinated, and 4) a treatment group in which Facebook users receive ads which include videos of health professionals encouraging them to get their most influential friends to help their friends get vaccinated. In treatments 3 and 4, participants will have the option to sign up to be a "vaccine ambassador," in which case they will get notifications when the study team posts new vaccine-related content, and will receive reminders about encouraging their friends to be vaccinated. The vaccine ambassadors will also be entered into a lottery to win prizes. The study team is building a website to host the videos of health professionals which answer common questions about Covid-19 vaccination. The investigators will measure engagement with the vaccine-related content as well as assess effects on vaccination rates at the county level.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
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Sponsor: as reported to ClinicalTrials.gov by Massachusetts Institute of Technology
Last refreshed: 25 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05182554.