NCT05180045 (LINKED-BP) is a NA clinical trial of LINKED-BP Program in Hypertension, sponsored by Johns Hopkins University.

Who is sponsoring NCT05180045?

NCT05180045 is sponsored by Johns Hopkins University.

What drugs are being tested in NCT05180045?

Interventions in NCT05180045: LINKED-BP Program.

What condition does NCT05180045 study?

NCT05180045 studies Hypertension, High Blood Pressure.

Is NCT05180045 still recruiting?

NCT05180045 is currently active, enrolled. Last updated 9 October 2025.

Last reviewed 2025-10-09 · How we verify

NCT05180045: LINKED-BP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Home Blood Pressure Telemonitoring LINKED With Community Health Workers to Improve Blood Pressure

Active, enrolled NA Last updated 9 October 2025

What this trial tests

NA trial testing LINKED-BP Program in Hypertension in 472 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

17 July 2023

Primary endpoint
1 June 2026

30 June 2026

Quick facts

Lead sponsor	Johns Hopkins University
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	472
Start date	17 July 2023
Primary completion	1 June 2026
Estimated completion	30 June 2026
Sites	20 locations across United States

Drugs / interventions tested

LINKED-BP Program

Conditions studied

Hypertension — all drugs for Hypertension →
High Blood Pressure — all drugs for High Blood Pressure →

Sponsor

Johns Hopkins University

Who can join

18 and older, any sex, with Hypertension or High Blood Pressure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The LINKED-BP Program is a patient-centered, multi-level intervention linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo) that links with all Bluetooth-enabled validated blood pressure (BP) devices, support from community health workers (CHWs), and BP measurement training at community health centers serving high-risk adults to prevent stage 2 hypertension (BP ≥ 140/90 mm Hg). The LINKED-BP Program study will recruit a total of 600 adults (30 from each practice) with elevated BP (120-129/\<80 mm Hg) or untreated stage 1 hypertension (130-139/80-89 mm Hg) across 20 community health centers or primary care practices serving high-risk adults. This cluster-randomized trial consists of two arms: (1) enhanced "usual care arm," wherein patients will be provided with Omron 10 series home BP monitors (HBPM) and will be managed by the patients' primary care clinicians as usual; and (2) the LINKED-BP Program or "intervention arm," which will include training of patients on HBPM, Sphygmo BP telemonitoring app, and CHW visits for education and counseling on lifestyle modification. The intervention period for each study participant is 12 months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Design and Rationale of the Home Blood Pressure Telemonitoring Linked with Community Health Workers to Improve Blood Pressure (LINKED-BP) Program.
Commodore-Mensah Y, Liu X, Ogungbe O, Ibe C, et al · · 2023 · cited 12× · PMID 37061796 · DOI 10.1093/ajh/hpad001

Verify or expand the search:

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Other Johns Hopkins University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05180045 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
Last refreshed: 9 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05180045.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing