NCT05171725 (MES-CoBraD) is a clinical trial of EEG,PSG in Dementia, sponsored by Neurological Institute of Athens.

Who is sponsoring NCT05171725?

NCT05171725 is sponsored by Neurological Institute of Athens.

What drugs are being tested in NCT05171725?

Interventions in NCT05171725: EEG,PSG, biosample collection (blood and CSF), neuropsychological testing, actigraphy, clinician assessment.

What condition does NCT05171725 study?

NCT05171725 studies Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder, Circadian Rhythm Disorders, Healthy.

Is NCT05171725 still recruiting?

NCT05171725 is currently completed. Last updated 2 April 2026.

Last reviewed 2026-04-02 · How we verify

NCT05171725: MES-CoBraD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders

Completed Last updated 2 April 2026

What this trial tests

trial testing EEG,PSG in Dementia in 635 participants. Completed in 30 September 2024.

Timeline

1 April 2021

Primary endpoint
30 September 2024

30 September 2024

Quick facts

Lead sponsor	Neurological Institute of Athens
Status	Completed
Study type	OBSERVATIONAL
Enrollment	635
Start date	1 April 2021
Primary completion	30 September 2024
Estimated completion	30 September 2024
Sites	4 locations across United Kingdom, Israel, Greece, Spain

Drugs / interventions tested

EEG,PSG
biosample collection (blood and CSF)
neuropsychological testing
actigraphy
clinician assessment

Conditions studied

Dementia — all drugs for Dementia →
Alzheimer Disease — all drugs for Alzheimer Disease →
Epilepsy — all drugs for Epilepsy →
Sleep Disorder — all drugs for Sleep Disorder →

Sponsor

Neurological Institute of Athens

Who can join

Eligibility, any sex, with Dementia or Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through comprehensive, cost-efficient, and fast protocols towards improving diagnostic accuracy and therapeutic outcomes in people with Complex Brain Disorders (CoBraD), as reflected in Neurocognitive (Dementia), Sleep, and Seizure (Epilepsy) disorders and their interdependence. It brings together internationally recognized experts in medicine, engineering, computer science, social health science, law, and marketing and communication from across Europe, and combines clinical information and scientific research in CoBraD with technical innovation in secure data-sharing platforms, artificial intelligence algorithms, and expert systems of precision and personalized care, with a primary focus on improving the quality of life of patients, their caregivers, and the society at large. It leverages RWD from diverse CoBraD populations across cultural, socioeconomic, educational, and health system backgrounds, with special attention on including vulnerable populations and minorities in an equitable manner and engaging key stakeholders to maximize project impact.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05171725 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Neurological Institute of Athens
Last refreshed: 2 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05171725.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing