NCT05170295 is a clinical trial in Intracranial Pressure Increase, sponsored by Ochsner Health System.

Who is sponsoring NCT05170295?

NCT05170295 is sponsored by Ochsner Health System.

What condition does NCT05170295 study?

NCT05170295 studies Intracranial Pressure Increase, Cerebral Edema.

Is NCT05170295 still recruiting?

NCT05170295 is currently completed. Last updated 27 December 2021.

Last reviewed 2021-12-27 · How we verify

NCT05170295

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Noninvasive Monitoring of Cerebral Blood Flow Autoregulation

Completed Last updated 27 December 2021

What this trial tests

trial in Intracranial Pressure Increase in 14 participants. Completed in 28 April 2021.

Timeline

18 April 2018

Primary endpoint
28 April 2021

28 April 2021

Quick facts

Lead sponsor	Ochsner Health System
Status	Completed
Study type	OBSERVATIONAL
Enrollment	14
Start date	18 April 2018
Primary completion	28 April 2021
Estimated completion	28 April 2021
Sites	1 location across United States

Conditions studied

Intracranial Pressure Increase — all drugs for Intracranial Pressure Increase →
Cerebral Edema — all drugs for Cerebral Edema →

Sponsor

Ochsner Health System — full company profile →

Who can join

18 and older, any sex, with Intracranial Pressure Increase or Cerebral Edema. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Rheoencephalography (REG) shows promise as a method for noninvasive neuromonitoring, because it reflects cerebrovascular reactivity. This protocol will study clinical and technical conditions required to use REG. Additionally, our goal is to study noninvasive peripheral bioimpedance pulse waveforms in order to substitute invasive SAP. A previous study demonstrated that REG can be used to detect spreading depolarization (SD), the early sign of brain metabolic disturbance. SD can be measured invasively with DC EEG amplifiers only. Our goal is to create an automatic notification function for REG monitoring indicating change of clinical conditions.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Noninvasive neuromonitoring with rheoencephalography: a case report.
Cannizzaro LA, Iwuchukwu I, Rahaman V, Hirzallah M, et al · · 2023 · cited 3× · PMID 36934402 · DOI 10.1007/s10877-023-00985-8

Verify or expand the search:

Other recruiting trials for Intracranial Pressure Increase

Currently open trials in the same condition.

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Other Ochsner Health System trials

Trials by the same sponsor.

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NCT06613191 — Colonoscopy and Antiplatelet Therapy Trial · Phase 4 · not yet recruiting
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05170295 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ochsner Health System
Last refreshed: 27 December 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05170295.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing