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NCT05167968: PHARE
Adherence of Diuretics in Pulmonary Hypertension
trial testing No intervention (Observational cohort) in Precapillary Pulmonary Hypertension in 227 participants. Completed in 24 January 2024.
24 January 2024
Quick facts
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 227 |
| Start date | 13 January 2022 |
| Primary completion | 24 January 2024 |
| Estimated completion | 24 January 2024 |
| Sites | 1 location across France |
Drugs / interventions tested
- No intervention (Observational cohort)
Conditions studied
- Precapillary Pulmonary Hypertension — all drugs for Precapillary Pulmonary Hypertension →
Sponsor
Assistance Publique - Hôpitaux de Paris — full company profile →
Who can join
18 and older, any sex, with Precapillary Pulmonary Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this prospective study, the investigators will implement a systematic assessment of adherence to diuretics in a cohort of patients with precapillary pulmonary hypertension. This study is designed to: * determine the overall adherence rates for diuretic regimen * determine the determinants of non-adherence to diuretics * assess the risk of PH worsening occurrence in the non-adhesion group
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Diuretic adherence in patients with pre-capillary pulmonary hypertension: insights from the PHARE study.
Le Bozec A, Cohen SD, Montani D, Boucly A, et al · · 2025 · PMID 41257177 · DOI 10.1183/23120541.00110-2025
Verify or expand the search:
- PubMed search for NCT05167968
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05167968 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assistance Publique - Hôpitaux de Paris
- Last refreshed: 11 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05167968.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing