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NCT05167968: PHARE

Adherence of Diuretics in Pulmonary Hypertension

Completed Last updated 11 February 2026
What this trial tests

trial testing No intervention (Observational cohort) in Precapillary Pulmonary Hypertension in 227 participants. Completed in 24 January 2024.

Timeline
13 January 2022
Primary endpoint
24 January 2024
24 January 2024

Quick facts

Lead sponsorAssistance Publique - Hôpitaux de Paris
StatusCompleted
Study typeOBSERVATIONAL
Enrollment227
Start date13 January 2022
Primary completion24 January 2024
Estimated completion24 January 2024
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Assistance Publique - Hôpitaux de Paris — full company profile →

Who can join

18 and older, any sex, with Precapillary Pulmonary Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this prospective study, the investigators will implement a systematic assessment of adherence to diuretics in a cohort of patients with precapillary pulmonary hypertension. This study is designed to: * determine the overall adherence rates for diuretic regimen * determine the determinants of non-adherence to diuretics * assess the risk of PH worsening occurrence in the non-adhesion group

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Diuretic adherence in patients with pre-capillary pulmonary hypertension: insights from the PHARE study.
    Le Bozec A, Cohen SD, Montani D, Boucly A, et al · · 2025 · PMID 41257177 · DOI 10.1183/23120541.00110-2025

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Other Assistance Publique - Hôpitaux de Paris trials

Trials by the same sponsor.

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05167968.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing