NCT05162417 is a NA clinical trial of Methylene Blue in Periodontal Diseases, sponsored by University of Sulaimani.

Who is sponsoring NCT05162417?

NCT05162417 is sponsored by University of Sulaimani.

What drugs are being tested in NCT05162417?

Interventions in NCT05162417: Methylene Blue, Toluidine Blue O.

What condition does NCT05162417 study?

NCT05162417 studies Periodontal Diseases, Periodontal Pocket.

Is NCT05162417 still recruiting?

NCT05162417 is currently completed. Last updated 29 November 2023.

Last reviewed 2023-11-29 · How we verify

NCT05162417

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Photodynamic in Periodontal Treatment

Completed NA Last updated 29 November 2023

What this trial tests

NA trial testing Methylene Blue in Periodontal Diseases in 18 participants. Completed in 1 April 2023.

Timeline

15 November 2021

Primary endpoint
1 November 2022

1 April 2023

Quick facts

Lead sponsor	University of Sulaimani
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	18
Start date	15 November 2021
Primary completion	1 November 2022
Estimated completion	1 April 2023
Sites	1 location across Iraq

Drugs / interventions tested

Methylene Blue (METHYLENE BLUE) — full drug profile →
Toluidine Blue O — full drug profile →

Conditions studied

Periodontal Diseases — all drugs for Periodontal Diseases →
Periodontal Pocket — all drugs for Periodontal Pocket →

Sponsor

University of Sulaimani

Who can join

18 and older, any sex, with Periodontal Diseases or Periodontal Pocket. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Dental biofilm is a primary etiological factor for periodontal diseases.(1) The bacterial biofilm would induce recruitment of leucocytes, neutrophils, and T lymphocytes and the secretion of antibodies, lipopolysaccharides, and chemical inflammatory mediators such as cytokines and chemokines.(2) Thus, periodontal diseases can cause tissue destruction and results in deterioration of clinical parameters measures such as periodontal pockets depth, clinical attachment loss, bleeding on probing, bone destruction, and resulting ultimately in tooth loss.(3)

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy of Non-Surgical Periodontal Therapy with Adjunctive Methylene Blue and Toluidine Blue O Mediated Photodynamic in Treatment of Periodontitis: A Randomized Clinical Trial.
Najm KK, Gul SS, Abdulkareem AA. · · 2024 · PMID 38804408 · DOI 10.3390/clinpract14030076

Verify or expand the search:

Other trials of Methylene Blue

Trials testing the same drug.

NCT06052956 — Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses · Phase 2 · not yet recruiting
NCT07494773 — Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection · Phase 1, PHASE2 · not yet recruiting
NCT07040540 — Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia · completed
NCT07169487 — Adjunctive Methylene Blue for Immunotherapy-related CRS and ICANS: Phase I Study · Phase 1 · recruiting
NCT06900140 — Adjunctive Methylene Blue in Septic Shock · Phase 3 · completed

Other recruiting trials for Periodontal Diseases

Currently open trials in the same condition.

NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
NCT07312045 — HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical T · recruiting
NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting

Other University of Sulaimani trials

Trials by the same sponsor.

NCT07234149 — Tooth Discoloration and Chairside Handling Time (Bonding-Debonding) in Flowable Versus Packable Composites for Clear Ali · NA · recruiting
NCT07142525 — Hybrid Osteoplasty Versus Osteotomy in Rhinoplasty · NA · not yet recruiting
NCT06719674 — Diode Laser as an Adjunct to Professional Mechanical Plaque Removal · NA · recruiting
NCT06719661 — The Impact of Clinical Pharmacist Intervention and Dapagliflozin as Add-On Therapy in the Management of Type 2 Diabetes · NA · completed
NCT06645041 — The Impact of Vitamin D Supplementation in Hypertensive Vitamin D Deficient Patients. · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05162417 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Sulaimani
Last refreshed: 29 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05162417.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing