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NCT05147376
Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances
EARLY_PHASE1 trial testing Curcumin mouthwash in Oral Ulcer in 70 participants. Completed in 7 August 2023.
7 August 2023
Quick facts
| Lead sponsor | Chulalongkorn University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 70 |
| Start date | 21 February 2022 |
| Primary completion | 7 August 2023 |
| Estimated completion | 7 August 2023 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Curcumin mouthwash — full drug profile →
- Placebo mouthwash — full drug profile →
Conditions studied
- Oral Ulcer — all drugs for Oral Ulcer →
- Orthodontic Appliances, Fixed — all drugs for Orthodontic Appliances, Fixed →
Sponsor
Chulalongkorn University
Who can join
Adults 12 to 30, any sex, with Oral Ulcer or Orthodontic Appliances, Fixed. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is a randomized controlled trial. The participants will be equally allocated into 2 groups to compare clinical effectiveness of curcumin mouthwash in fixed orthodontic patients during the first month of treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effectiveness of curcumin mouthwash in preventing traumatic ulcers in orthodontic patients.
Somprajob C, Auychai P, Chavanavesh J, Suttamanatwong S. · · 2025 · cited 1× · PMID 41185016 · DOI 10.1186/s12903-025-07141-5
Verify or expand the search:
- PubMed search for NCT05147376
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Oral Ulcer
Currently open trials in the same condition.
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Other Chulalongkorn University trials
Trials by the same sponsor.
- NCT07458659 — Clinical Study of BCMA-Targeted CAR T-Cell Injection in the Treatment of Patients With Relapsed/Refractory Multiple Myel · EARLY_PHASE1 · not yet recruiting
- NCT07346118 — Fluid Balance Guided by Modified Venous Excess Ultrasonography Versus Standard Care in Patients With Acute Kidney Injury · NA · not yet recruiting
- NCT07388862 — Comparison of Treatment Outcome of Pulpotomy With Versus Without Dental Operating Microscope in Carious Mature Permanent · EARLY_PHASE1 · not yet recruiting
- NCT07373977 — Comparison of Postoperative Pain After Pulpotomy Performed With Versus Without Dental Operating Microscope in Carious Ma · EARLY_PHASE1 · not yet recruiting
- NCT07078929 — Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05147376 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chulalongkorn University
- Last refreshed: 21 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05147376.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing