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Placebo Mouthwash
Placebo mouthwash has no active pharmaceutical ingredient and produces therapeutic effects solely through placebo mechanisms.
Placebo mouthwash has no active pharmaceutical ingredient and produces therapeutic effects solely through placebo mechanisms. Used for Control comparator in clinical trials for oral health conditions.
At a glance
| Generic name | Placebo Mouthwash |
|---|---|
| Also known as | Sterile Water, 0.0% HP Mouthwash, placebo, Mouthwash, Peridex mouthwash without chlorhexidine. |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University |
| Modality | Small molecule |
| Therapeutic area | Oral Health / Dentistry |
| Phase | FDA-approved |
Mechanism of action
As a placebo formulation, any observed clinical benefits arise from patient expectation, psychological factors, and the ritual of treatment rather than from a specific pharmacological action. Placebo mouthwashes are typically used in clinical research settings as control comparators to evaluate the true efficacy of active oral care products.
Approved indications
- Control comparator in clinical trials for oral health conditions
Common side effects
Key clinical trials
- Effects of Different Caffeine Forms on Aerobic and Anaerobic Exercise Performance (NA)
- Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients (PHASE2)
- PMPR and Chlorhexidine on Periodontal Disease and Vascular Function (NA)
- Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients. (PHASE2)
- Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients (NA)
- Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (PHASE3)
- Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH and Its Role in Improving Oral Hygiene and Gingival Health. In Situ Randomized Double-Blind Placebo CT (PHASE1)
- Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
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