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NCT05142904: RABITO
Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules
Phase 3 trial testing Radiofrequency ablation in Thyroid Nodule, Toxic or With Hyperthyroidism in 40 participants. Terminated before completion.
1 November 2024
Quick facts
| Lead sponsor | Rijnstate Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 17 November 2021 |
| Primary completion | 1 November 2024 |
| Estimated completion | 1 November 2024 |
| Sites | 14 locations across Netherlands |
Drugs / interventions tested
- Radiofrequency ablation
- Radioactive iodine — full drug profile →
- Radioactive iodine — full drug profile →
Conditions studied
- Thyroid Nodule, Toxic or With Hyperthyroidism — all drugs for Thyroid Nodule, Toxic or With Hyperthyroidism →
- Autonomous Thyroid Function — all drugs for Autonomous Thyroid Function →
- Thyroid Nodule; Hyperthyroidism — all drugs for Thyroid Nodule; Hyperthyroidism →
- Radiofrequency Ablation — all drugs for Radiofrequency Ablation →
Sponsor
Rijnstate Hospital
Who can join
18 and older, any sex, with Thyroid Nodule, Toxic or With Hyperthyroidism or Autonomous Thyroid Function. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to compare treatment of hyperthyroidism with radiofrequency ablation or I-131 for solitary autonomous thyroid nodules.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05142904
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Rijnstate Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05142904 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rijnstate Hospital
- Last refreshed: 17 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05142904.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing