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NCT05141773: CUFFAID
Artificial Intelligence Aid Systems and Endocuff in Colorectal Adenoma Detection
NA trial testing Computed adenoma detection system (CADe) plus endocuff in Adenoma Detection Rate in 696 participants. Completed in 30 April 2023.
30 April 2023
Quick facts
| Lead sponsor | Hospital Universitario de Canarias |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 696 |
| Start date | 1 November 2022 |
| Primary completion | 30 April 2023 |
| Estimated completion | 30 April 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Computed adenoma detection system (CADe) plus endocuff
- Endocuff
Conditions studied
- Adenoma Detection Rate — all drugs for Adenoma Detection Rate →
Sponsor
Hospital Universitario de Canarias
Who can join
18 and older, any sex, with Adenoma Detection Rate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main purpose of the study to evaluate the usefulness of the Endo-AID artificial intelligence system combined with endocuff compared with endocuff in the detection of colorectal adenomas in consecutive patients for outpatient colonoscopy. The secondary aims were: * To evaluate the benefit of Endo-AID and endocuff in adenoma detection rate by comparing endoscopists with high and low adenoma detection rate. * To evaluate serrated detection rate, advanced adenoma detection rate, adenoma detection rate according to the size (\<= 5mm, 6-9mm,\> = 10mm) and number of adenomas by colonoscopy. Stratification by location and morphology.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Computer-assisted adenoma detection colonoscopy with an ENDO-AID artificial intelligence system and Endocuff- versus Endocuff-assisted colonoscopy: A randomized controlled trial.
Gimeno-García AZ, Hernández A, Hernández Negrin D, Rodríguez E, et al · · 2026 · PMID 41935575 · DOI 10.1016/j.gastrohep.2026.502757
Verify or expand the search:
- PubMed search for NCT05141773
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Adenoma Detection Rate
Currently open trials in the same condition.
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- NCT06678477 — Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test · NA · recruiting
- NCT07076966 — Comparison of Adenoma Detection Rate in 3D vs. 2D Surveillance Colonoscopy · NA · recruiting
- NCT05863208 — Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision · NA · recruiting
- NCT05125939 — Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study · recruiting
Other Hospital Universitario de Canarias trials
Trials by the same sponsor.
- NCT05956119 — Effectiveness of Dry Needling for Improving Gait in the Patient With Multiple Sclerosis · NA · completed
- NCT05553977 — Artificial Intelligence and Bowel Cleansing Quality · unknown
- NCT04945044 — Artificial Intelligence Aid Systems in Colorectal Adenoma Detection · NA · completed
- NCT05053984 — Ultrasound-Guided Percutaneous Neuromodulation in Spasticity · NA · unknown
- NCT04702646 — Patient and Colonoscopy Cleansing Quality Agreement · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05141773 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Universitario de Canarias
- Last refreshed: 24 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05141773.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing