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NCT06961149
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
NA trial testing Chromoendoscopy with indigo carmine solution spray in Colonic Polyps in 352 participants. Currently enrolling.
31 January 2026
Quick facts
| Lead sponsor | Shandong University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 352 |
| Start date | 8 April 2025 |
| Primary completion | 31 January 2026 |
| Estimated completion | 1 April 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Chromoendoscopy with indigo carmine solution spray
- Linked-color imaging endoscopy
Conditions studied
- Colonic Polyps — all drugs for Colonic Polyps →
- Adenomatous Polyps — all drugs for Adenomatous Polyps →
- Adenoma Detection Rate — all drugs for Adenoma Detection Rate →
- Chromoendoscopy — all drugs for Chromoendoscopy →
Sponsor
Shandong University
Who can join
Adults 45 to 85, any sex, with Colonic Polyps or Adenomatous Polyps. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06961149
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Related trials
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Currently open trials in the same condition.
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Other Shandong University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06961149 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shandong University
- Last refreshed: 7 May 2025
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