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NCT05141487
Feasibility of Triggered Sacral Neuromodulation for Neurogenic Bladder
trial testing UroMonitor in Urinary Incontinence in 16 participants. Currently enrolling.
30 October 2026
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 16 |
| Start date | 3 October 2022 |
| Primary completion | 30 October 2026 |
| Estimated completion | 30 October 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- UroMonitor
- ASCU
Conditions studied
- Urinary Incontinence — all drugs for Urinary Incontinence →
- Urinary Bladder, Neurogenic — all drugs for Urinary Bladder, Neurogenic →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
18 and older, any sex, with Urinary Incontinence or Urinary Bladder, Neurogenic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Incontinence associates with military service and post-traumatic stress disorder in both male and female Veterans. Neurogenic detrusor overactivity (NDO) is caused by spinal cord injury or disorder, or peripheral neurodegenerative conditions, and causes urine leakage at low volumes. NDO is disproportionately experienced by Veterans and treatment effectiveness varies greatly between individuals. This project will demonstrate the feasibility of a new type of nerve stimulation-triggered sacral neuromodulation-to treat NDO in Veterans. A wireless bladder sensor will be inserted into the bladder to transmit a feedback signal enabling stimulation from a percutaneous lead. The wireless sensor will also measure NDO symptoms during simulated activities of daily living without catheters. Catheter-free detection of bladder activity will improve the outcomes of neuromodulation evaluations for Veterans with NDO. Future work could use the triggered neuromodulation system to study other methods of nerve stimulation to treat bladder, bowel, or sexual dysfunction.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05141487
- Europe PMC full search
- ASCO Meeting Library
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Other VA Office of Research and Development trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05141487 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 15 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05141487.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing