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NCT05133687
The Hemodynamic Effects of Different Volumes of Bupivacaine 0.25% Caudal Blocks in Pediatrics Undergoing Lower Abdominal Surgeries as Measured by Electrical Cardiometry
Phase 3 trial testing Bupivacaine Hydrochloride in Anesthesia, Caudal in 105 participants. Completed in 30 May 2022.
30 May 2022
Quick facts
| Lead sponsor | Kasr El Aini Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | diagnostic |
| Enrollment | 105 |
| Start date | 15 November 2021 |
| Primary completion | 30 May 2022 |
| Estimated completion | 30 May 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Bupivacaine Hydrochloride (Bupivacaine Hydrochloride) — full drug profile →
Conditions studied
- Anesthesia, Caudal — all drugs for Anesthesia, Caudal →
- Pediatrics — all drugs for Pediatrics →
Sponsor
Kasr El Aini Hospital
Who can join
Adults 1 to 8, any sex, with Anesthesia, Caudal or Pediatrics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized, controlled study is designed to estimate the effects of different volumes of plain bupivacaine 0.25% caudal block on different hemodynamic parameters assessed by electrical cardiometry.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of different volumes of bupivacaine 0.25% caudal blocks on cardiac index measured by electrical cardiometry in children undergoing elective lower abdominal surgeries: A randomised controlled trial.
Sarhan K, Gebreel M, Raouf A, Reda I, et al · · 2025 · cited 1× · PMID 40161906 · DOI 10.4103/ija.ija_858_24
Verify or expand the search:
- PubMed search for NCT05133687
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bupivacaine Hydrochloride
Trials testing the same drug.
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- NCT06575699 — Rectus Sheath Block for Analgesia After Gynecological Laparotomy · Phase 4 · completed
- NCT06577233 — Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis · Phase 4 · recruiting
- NCT06569953 — Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chron · Phase 4 · recruiting
Other Kasr El Aini Hospital trials
Trials by the same sponsor.
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- NCT07274280 — Comparative Evaluation of Ambu AuraGain, LarySeal Pro and I-gel in Pediatric Airway Management for Day-Case Surgery Unde · NA · not yet recruiting
- NCT07348146 — Hand-Sewn vs. Stapled Anastomosis in SADI-S: Early Postoperative Complications. · NA · enrolling by invitation
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05133687 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kasr El Aini Hospital
- Last refreshed: 9 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05133687.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing