NCT05128981 (MI-CBT) is a NA clinical trial of MI-CBT in Myocardial Infarction, sponsored by Karolinska Institutet.

Who is sponsoring NCT05128981?

NCT05128981 is sponsored by Karolinska Institutet.

What drugs are being tested in NCT05128981?

Interventions in NCT05128981: MI-CBT.

What condition does NCT05128981 study?

NCT05128981 studies Myocardial Infarction, Cardiac Anxiety, CBT, Exposure.

Is NCT05128981 still recruiting?

NCT05128981 is currently completed. Last updated 10 January 2023.

Last reviewed 2023-01-10 · How we verify

NCT05128981: MI-CBT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Internet-delivered Cognitive Behavioral Therapy Following Myocardial Infarction

Completed NA Last updated 10 January 2023

What this trial tests

NA trial testing MI-CBT in Myocardial Infarction in 23 participants. Completed in 10 December 2022.

Timeline

28 October 2021

Primary endpoint
10 December 2022

10 December 2022

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	23
Start date	28 October 2021
Primary completion	10 December 2022
Estimated completion	10 December 2022
Sites	1 location across Sweden

Drugs / interventions tested

MI-CBT

Conditions studied

Myocardial Infarction — all drugs for Myocardial Infarction →
Cardiac Anxiety — all drugs for Cardiac Anxiety →
CBT — all drugs for CBT →
Exposure — all drugs for Exposure →

Sponsor

Karolinska Institutet

Who can join

Adults 18 to 75, any sex, with Myocardial Infarction or Cardiac Anxiety. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Myocardial infarction (MI) is one of the leading cause s of health loss globally, representing a large proportion of general disability. Anxiety and depression occur in 20-30 percent of patients following MI and have been identified as risk factors for recurrent adverse cardiac event. The purpose of our this study is to develop and evaluate a disease specific cognitive behavioral therapy (C BT) protocol to reduce cardia anxiety, depression, increase physical inactivity and quality of life (Q oL) in patients following MI

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Cognitive behavioural therapy targeting cardiac anxiety post-myocardial infarction: results from two sequential pilot studies.
Johnsson A, Ljótsson B, Liliequist BE, Skúladóttir H, et al · · 2025 · cited 5× · PMID 40177506 · DOI 10.1093/ehjopen/oeaf020

Verify or expand the search:

Other trials of MI-CBT

Trials testing the same drug.

NCT05594238 — Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders · NA · active not recruiting
NCT05580718 — Online Cognitive Behavioral Therapy Targeting Cardiac Anxiety · NA · active not recruiting
NCT04649307 — Cognitive Behavioral Therapy Following Myocardial Infarction · NA · completed
NCT01337973 — Preventing Violence Among Veterans in Substance Use Disorder Treatment · NA · completed

Other recruiting trials for Myocardial Infarction

Currently open trials in the same condition.

NCT07257198 — Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone · Phase 3 · recruiting
NCT07402642 — Effect of Early Educational Intervention on Cardiovascular Risk Factors After Acute Coronary Syndrome · NA · recruiting
NCT07301034 — A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, · Phase 3 · recruiting
NCT07142265 — Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients · recruiting
NCT07138911 — Effect of Home-based Exercise Plan Mediated by Use of Digital Health App on Kinesiophobia and Functional Capacity · NA · recruiting

Other Karolinska Institutet trials

Trials by the same sponsor.

NCT06359262 — Evaluating the Hope@School Prevention Program · NA · not yet recruiting
NCT07289490 — Bilateral vs Unilateral Inguinal Hernia Repairs With an Asymptomatic Inguinal Hernia in Bilateral Hernias · NA · not yet recruiting
NCT06894264 — Emotion Processing and Regulation in People With Intellectual Disability · NA · not yet recruiting
NCT07494266 — Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited · NA · not yet recruiting
NCT07442032 — Cardiovascular Phenotypes in Sepsis · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05128981 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
Last refreshed: 10 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05128981.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing