Who is sponsoring NCT05107310?

NCT05107310 is sponsored by Karolinska Institutet.

What drugs are being tested in NCT05107310?

Interventions in NCT05107310: Pedicle screws insertion by free hand technique, Pedicle screws insertion using ARSN, Pedicle screws insertion using IRSN.

What condition does NCT05107310 study?

NCT05107310 studies Scoliosis, Kyphosis.

Is NCT05107310 still recruiting?

NCT05107310 is currently active, enrolled. Last updated 21 February 2025.

Last reviewed 2025-02-21 · How we verify

NCT05107310: SPINAV

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Spinal Navigation Trial - Surgical Navigation or Free Hand Technique in Spine Surgery

Active, enrolled NA Last updated 21 February 2025

What this trial tests

NA trial testing Pedicle screws insertion by free hand technique in Scoliosis in 62 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

18 January 2022

Primary endpoint
30 June 2024

30 June 2029

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	62
Start date	18 January 2022
Primary completion	30 June 2024
Estimated completion	30 June 2029
Sites	1 location across Sweden

Drugs / interventions tested

Pedicle screws insertion by free hand technique
Pedicle screws insertion using ARSN
Pedicle screws insertion using IRSN

Conditions studied

Scoliosis — all drugs for Scoliosis →
Kyphosis — all drugs for Kyphosis →

Sponsor

Karolinska Institutet

Who can join

12 and older, any sex, with Scoliosis or Kyphosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The spinal navigation trial (SPINAV) is a randomized controlled trial (RCT) evaluating the use of computer-assisted navigation in surgery for spinal deformity

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Augmented Reality in Minimally Invasive Spinal Interventions: Current Use and Future Directions.
Pruthi A, Alexander T, Mengaliyeva A, Kota N, et al · · 2025 · cited 2× · PMID 40190981 · DOI 10.7759/cureus.80119
Study protocol: the SPInal NAVigation (SPINAV) trial - comparison of augmented reality surgical navigation, conventional image-guided navigation, and free-hand technique for pedicle screw placement in spinal deformity surgery.
El-Hajj VG, Charalampidis A, Fell D, Edström E, et al · · 2025 · cited 1× · PMID 40457280 · DOI 10.1186/s12891-025-08817-3

Verify or expand the search:

Other recruiting trials for Scoliosis

Currently open trials in the same condition.

NCT07447193 — Investigation of Pain Perception According to Gender in Individuals With Scoliosis · NA · recruiting
NCT07059663 — Synergic Effects of Schroth Method With and Without Core Stabilization Exercises in Idiopathic Scoliosis Patients · NA · recruiting
NCT06540885 — A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery · Phase 4 · recruiting
NCT06242821 — Yoga for Back Pain in Adolescent Scoliosis · NA · recruiting
NCT06451562 — Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery · NA · recruiting

Other Karolinska Institutet trials

Trials by the same sponsor.

NCT06359262 — Evaluating the Hope@School Prevention Program · NA · not yet recruiting
NCT07289490 — Bilateral vs Unilateral Inguinal Hernia Repairs With an Asymptomatic Inguinal Hernia in Bilateral Hernias · NA · not yet recruiting
NCT06894264 — Emotion Processing and Regulation in People With Intellectual Disability · NA · not yet recruiting
NCT07494266 — Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited · NA · not yet recruiting
NCT07442032 — Cardiovascular Phenotypes in Sepsis · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05107310 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
Last refreshed: 21 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05107310.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing