NCT05081843

Pittsburgh and Rural Area High School Tobacco Prevention

Completed NA Results posted Last updated 4 June 2025

What this trial tests

NA trial testing AD IT UP media literacy intervention in Adolescent Behavior in 318 participants. Completed in 1 March 2024.

Timeline

1 March 2022

Primary endpoint
1 March 2024

1 March 2024

Quick facts

Lead sponsor	University of Pittsburgh
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	318
Start date	1 March 2022
Primary completion	1 March 2024
Estimated completion	1 March 2024
Sites	1 location across United States

Drugs / interventions tested

• AD IT UP media literacy intervention
• Usual health education curriculum

Conditions studied

• Adolescent Behavior — all drugs for Adolescent Behavior →
• Tobacco Use — all drugs for Tobacco Use →
• E-Cig Use — all drugs for E-Cig Use →

Sponsor

University of Pittsburgh

Who can join

Adults 13 to 17, any sex, with Adolescent Behavior or Tobacco Use. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Percentage of Eligible 9th Grade Students Recruited to Participate in the Study Primary · 1 month

Parents will be asked to return an opt out form if they do not want their student to participate. Students will provide assent if they wish to participate. Recruitment will be determined by calculating the percentage of eligible 9th grade students not opted out by their parents that also provide assent.

Group	Value	95% CI
Usual Health Education Curriculum	158
Usual Health Education Curriculum Plus Intervention	160

Percentage of Participants Retained Through the Final Data Collection Primary · 12 months

Retention will be calculated as the percentage of 9th grade students who completed the baseline survey and also completed the 12 month follow-up survey.

Group	Value	95% CI
Usual Health Education Curriculum	23
Usual Health Education Curriculum Plus Intervention	15

Percentage of Participants Indicating Moderate to High Acceptability of the AD IT UP Program Primary · post-test immediately following completion of the intervention

Acceptability of the intervention will be assessed with closed-ended and open-ended items on the post-test survey immediately following completion of the intervention. Students will be asked on a 5-point Likert scale with responses ranging from Strongly Agree to Strongly Disagree (with a neutral middle) their agreement about the following: "I enjoyed AD IT UP," "I understood AD IT UP," "AD IT UP was easy to use," "I tried my hardest when I was doing AD IT UP," "I think AD IT UP would be helpful to other kids my age," "I would recommend AD IT UP to a friend," and "I agree with AD IT UP's messa

Agreed with "I understood AD IT UP"

Group	Value	95% CI
Usual Health Education Curriculum Plus Intervention	81

Agreed with "AD IT UP was easy to use"

Group	Value	95% CI
Usual Health Education Curriculum Plus Intervention	62

Agreed with "I tried my hardest when using AD IT UP"

Group	Value	95% CI
Usual Health Education Curriculum Plus Intervention	66

Agreed with "UP would be helpful to other kids my age"

Group	Value	95% CI
Usual Health Education Curriculum Plus Intervention	64

Agreed with "I agree with AD IT UP's message"

Group	Value	95% CI
Usual Health Education Curriculum Plus Intervention	82

Changes in Intention to Use Tobacco Products Secondary · baseline vs. 12 month follow-up

Items used in this analysis: If one of your best friends offered you a \[NTP\], would you smoke/use it? This item was repeated for cigarettes, hookah, e-cigarettes, and cigars/cigarillos. This item included the a 4-item response scale ranging from Definitely No to Definitely Yes for each of the 4 NTPs. Susceptibility was considered any response except "Definitely No" and totaled for a possible range of 0 to 4. Answering anything other than "Definitely No" on any item is considered susceptible to using tobacco products. These were totaled for a possible range of 0 to 4, with higher scores r

Group	Value	95% CI
Usual Health Education Curriculum	0.386	± 0.997
Usual Health Education Curriculum Plus Intervention	0.419	± 1.116

Changes in Attitudes Toward Tobacco Products Secondary · baseline vs. 12 month follow-up

Items to measure attitudes toward tobacco products will be included in all 4 surveys. These items include the following with a 10-item response scale ranging from Strongly Disagree to Strongly Agree. E-cigarettes are not as bad for your health as other products. Using tobacco products at parties is fun. (added: Using e-cigarettes at parties is fun) Tobacco products help you deal with problems or stress. Smoking helps people stay thin. People who use e-cigarettes are more fun to be around than people who don't use e-cigarettes. If someone starts using tobacco products every day, it is very ha

Group	Value	95% CI
Usual Health Education Curriculum	3.09	± 1.98
Usual Health Education Curriculum Plus Intervention	2.91	± 1.25

Changes in Normative Beliefs About Tobacco Products Secondary · baseline vs. 12 month follow-up

Items to measure normative beliefs about tobacco products will be included in all 4 surveys. These items ask participants their rate how acceptable the following statements are among their friends using a 10-item response scale ranging from Very Acceptable to Very Unacceptable: It is OK for people your age to smoke cigarettes. It is OK for people your age to use e-cigarettes. It is OK for people your age to use hookahs. It is OK for people your age to smoke cigars or cigarillos. A wealthy person is more likely to use tobacco products than a poor person. A successful person is more likely to u

Group	Value	95% CI
Usual Health Education Curriculum	2.43	± 2.07
Usual Health Education Curriculum Plus Intervention	2.25	± 1.29

Change in Tobacco-related Media Literacy Secondary · baseline vs. 12 month follow-up

Items to measure tobacco-related media literacy will be adapted from the Smoking Media Literacy Scale and included in all 4 surveys. The response scale for these 8 items is a 10-item scale from "Strongly Disagree" to "Strongly Agree." Changes in media literacy will be determined by the average increase or decrease in agreement with these items. These items will be assessed individually, as well as an overall scale (range 0-80, with higher scores indicating a worse outcome).

Group	Value	95% CI
Usual Health Education Curriculum	7.98	± 1.68
Usual Health Education Curriculum Plus Intervention	8.89	± 1.79

Sponsor's own description

This research project will explore the feasibility and acceptability of a web-based media literacy tobacco prevention program. The project will be conducted with 9th graders in two schools in the Pittsburgh area.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Interventions to prevent or cease electronic cigarette use in children and adolescents.
   Barnes C, Turon H, McCrabb S, Hodder RK, et al · · 2023 · cited 14× · PMID 37965949 · DOI 10.1002/14651858.cd015511.pub2