Who is sponsoring NCT06576076?

NCT06576076 is sponsored by Massachusetts General Hospital.

What drugs are being tested in NCT06576076?

Interventions in NCT06576076: Contingency management for cannabis abstinence.

What condition does NCT06576076 study?

NCT06576076 studies Cannabis Use, Depression, Suicidal Ideation, Adolescent Behavior.

Is NCT06576076 still recruiting?

NCT06576076 is currently recruiting now. Last updated 3 March 2026.

Last reviewed 2026-03-03 · How we verify

NCT06576076: CLEAR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cannabis, Linked Emotions, and Adolescent Risk Study

Recruiting now NA Last updated 3 March 2026

What this trial tests

NA trial testing Contingency management for cannabis abstinence in Cannabis Use in 200 participants. Currently enrolling.

Timeline

18 February 2025

Primary endpoint
30 April 2029

30 April 2029

Quick facts

Lead sponsor	Massachusetts General Hospital
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	200
Start date	18 February 2025
Primary completion	30 April 2029
Estimated completion	30 April 2029
Sites	1 location across United States

Drugs / interventions tested

Contingency management for cannabis abstinence

Conditions studied

Cannabis Use — all drugs for Cannabis Use →
Depression — all drugs for Depression →
Suicidal Ideation — all drugs for Suicidal Ideation →
Adolescent Behavior — all drugs for Adolescent Behavior →

Sponsor

Massachusetts General Hospital

Who can join

Adults 12 to 18, any sex, with Cannabis Use or Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of scalable, individualized, accessible, and affordable interventions aimed to reduce depression and suicide risk among adolescents.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Characterizing proximal risk for depressive symptoms and suicidal ideation with acute cannabis use and withdrawal among adolescents using ecological momentary assessment: Study protocol.
Feibus I, Mahiques MB, Costello M, Potter K, et al · · 2025 · PMID 41411314 · DOI 10.1371/journal.pone.0338790

Verify or expand the search:

Other recruiting trials for Cannabis Use

Currently open trials in the same condition.

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Other Massachusetts General Hospital trials

Trials by the same sponsor.

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NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06576076 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
Last refreshed: 3 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06576076.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing