NCT05063461 is a NA clinical trial of Tetanic stimulation in General Anesthesia, sponsored by Beijing Chao Yang Hospital.

Who is sponsoring NCT05063461?

NCT05063461 is sponsored by Beijing Chao Yang Hospital.

What drugs are being tested in NCT05063461?

Interventions in NCT05063461: Tetanic stimulation, Skin incision.

What condition does NCT05063461 study?

NCT05063461 studies General Anesthesia.

Is NCT05063461 still recruiting?

NCT05063461 is currently completed. Last updated 22 March 2023.

Last reviewed 2023-03-22 · How we verify

NCT05063461

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Analgesia Nociception Index With Varying Remifentanil Concentrations Under Sevoflurane

Completed NA Last updated 22 March 2023

What this trial tests

NA trial testing Tetanic stimulation in General Anesthesia in 32 participants. Completed in 1 March 2023.

Timeline

25 September 2021

Primary endpoint
28 February 2023

1 March 2023

Quick facts

Lead sponsor	Beijing Chao Yang Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	32
Start date	25 September 2021
Primary completion	28 February 2023
Estimated completion	1 March 2023
Sites	1 location across China

Drugs / interventions tested

Tetanic stimulation
Skin incision

Conditions studied

General Anesthesia — all drugs for General Anesthesia →

Sponsor

Beijing Chao Yang Hospital

Who can join

Adults 18 to 65, any sex, with General Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Analgesia Nociception Index（ANI）which is derived from heart rate variability can be used to detect noxious stimulation during propofol while changing remifentanil concentrations. The aim of this study is to verify the effectiveness of ANI predictability for actual surgical noxious stimuli while satisfying the individual analgesic status by pre-tetanus-induced ANI determination during sevoflurane while changing remifentanil concentrations.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of the effectiveness of analgesia nociception index (ANI) predictability for surgical stimuli under personal analgesic sufficiency status (PASS) measured by pre-tetanus-induced ANI: a pilot study.
Yang L, Wang X, Wen H. · · 2023 · cited 1× · PMID 37418059 · DOI 10.1007/s10877-023-01044-y

Verify or expand the search:

Other trials of Tetanic stimulation

Trials testing the same drug.

NCT04786275 — Evaluation of the Nociception Guided by NoL Index and PK of Fentanyl in Pediatric Patients Under General Anesthesia · completed

Other recruiting trials for General Anesthesia

Currently open trials in the same condition.

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NCT07074730 — General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty · NA · recruiting

Other Beijing Chao Yang Hospital trials

Trials by the same sponsor.

NCT07520305 — Efficacy Heterogeneity of Lactobacillus Paracasei LC19 on Type 2 Diabetes · NA · not yet recruiting
NCT07490925 — Transpulmonary Pressure-guided Mechanical Ventilation Strategy in Right Ventricular Protection in Patients With ARDS · NA · not yet recruiting
NCT07382986 — IMPACT COPD Cohort (China) · recruiting
NCT07323134 — The Effect of Semaglutide on the Intestinal Flora in Obesity · not yet recruiting
NCT07049692 — Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05063461 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beijing Chao Yang Hospital
Last refreshed: 22 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05063461.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing