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NCT05062967
Evaluation of Orthohepevirus C Infection as an Emerging Cause of Zoonotic Origin Disease
trial in Hepatitis in 3,257 participants. Status unknown.
1 October 2024
Quick facts
| Lead sponsor | Maimónides Biomedical Research Institute of Córdoba |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 3,257 |
| Start date | 1 January 2022 |
| Primary completion | 1 October 2024 |
| Estimated completion | 1 December 2024 |
| Sites | 10 locations across Spain |
Conditions studied
- Hepatitis — all drugs for Hepatitis →
- Liver Diseases — all drugs for Liver Diseases →
- Acute Hepatitis — all drugs for Acute Hepatitis →
- Chronic Hepatitis — all drugs for Chronic Hepatitis →
Sponsor
Maimónides Biomedical Research Institute of Córdoba
Who can join
18 and older, any sex, with Hepatitis or Liver Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main objective of this study is to evaluate the prevalence and the clinical impact of Orthohepevirus C infection in different human populations, and to determine its zoonotic origin comparing the sequences obtained in both human and animal populations. This is an ambispective study where Orthohepevirus C infection will be evaluated in four high risk human population: i) patients with acute hepatitis, ii) patients with positive IgM antibody against Hepatitis E virus infection with undetectable viral load, iii) HIV infected individuals, and iv) solid organ transplant recipients. Furthermore, we will analyze three animal populations: i) suburban rodents, ii) domestic rodents, iii) wild carnivores. Viral sequences identified in both human and animal populations will be compared to evaluate the zoonotic origin of the infections.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Rat hepatitis E virus as an aetiological agent of acute hepatitis of unknown origin.
Caballero-Gómez J, Casares-Jiménez M, Gallo-Marín M, Pereira-Pardo S, et al · · 2025 · cited 20× · PMID 40020930 · DOI 10.1016/j.jhep.2025.02.027
Verify or expand the search:
- PubMed search for NCT05062967
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Maimónides Biomedical Research Institute of Córdoba trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05062967 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Maimónides Biomedical Research Institute of Córdoba
- Last refreshed: 30 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05062967.
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