NCT05052450

Factors Associated With Mortality, Morbidity and Prognosis in Dementia Patients

Completed Last updated 22 September 2021

What this trial tests

trial testing Observational in Dementia in 1,000 participants. Completed in 31 December 2020.

Timeline

1 January 2000

Primary endpoint
31 December 2020

31 December 2020

Quick facts

Lead sponsor	Gulhane Training and Research Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 January 2000
Primary completion	31 December 2020
Estimated completion	31 December 2020

Drugs / interventions tested

• Observational — full drug profile →

Conditions studied

• Dementia — all drugs for Dementia →
• Dementia, Vascular — all drugs for Dementia, Vascular →
• Dementia With Lewy Bodies — all drugs for Dementia With Lewy Bodies →
• Dementia of Alzheimer Type — all drugs for Dementia of Alzheimer Type →

Sponsor

Gulhane Training and Research Hospital

Who can join

60 and older, any sex, with Dementia or Dementia, Vascular. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Dementia; It is a chronic syndrome characterized by a general and progressive deterioration in cognition, including memory, orientation, language, and comprehension. The prognosis of this progressive and neurodegenerative disease after diagnosis may differ between individuals. In its broadest sense, the prognosis after a diagnosis of dementia; can be defined by shortening of life span, high level of cognitive and functional loss, decrease in quality of life and increased need for care. However, the prognosis of different types of dementia is highly variable. Because it is the most common type of dementia, studies are usually on Alzheimer's disease. It constitutes 50-75% of total dementia cases. Vascular dementia is the second most common cause of dementia and accounts for approximately 15% of dementia cases. Dementia with Lewy bodies constitutes 10-20% of the total dementia patients and ranks second among degenerative dementia types. Frontotemporal dementia, which mimics psychiatric disorders and has prominent behavioural problems, and Parkinson's disease-associated dementia, which is characterized by cognitive impairment that can be added to the existing picture in Parkinson's patients, are also counted among other types of dementia. Prognosis-related data on dementia types other than Alzheimer's disease are limited in the literature. Determining the prognosis is important to support patients, anticipate long-term health problems, plan physician and healthcare provision, and support patients with dementia.In view of the lack of sufficient data on dementia types other than Alzheimer's disease, it is aimed to contribute to the literature on this subject and to determine the factors that may affect prognosis, morbidity and mortality in patients belonging to all dementia types.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Assessment of clinical features and coexisting geriatric syndromes in newly diagnosed dementia with Lewy bodies: a retrospective study in a tertiary geriatrics setting in Turkey.
   Naharci MI, Kayahan Satis N, Ozsurekci C, Tasci I. · · 2023 · cited 6× · PMID 36512254 · DOI 10.1007/s41999-022-00727-0