NCT07039370 (PROMET_TMS) is a NA clinical trial of TMS in Major Depression Disorder, sponsored by Gulhane Training and Research Hospital.

Who is sponsoring NCT07039370?

NCT07039370 is sponsored by Gulhane Training and Research Hospital.

What drugs are being tested in NCT07039370?

Interventions in NCT07039370: TMS.

What condition does NCT07039370 study?

NCT07039370 studies Major Depression Disorder.

Is NCT07039370 still recruiting?

NCT07039370 is currently recruiting now. Last updated 26 June 2025.

Last reviewed 2025-06-26 · How we verify

NCT07039370: PROMET_TMS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Molecular Signatures of TMS Response in Treatment-Resistant Depression

Recruiting now NA Last updated 26 June 2025

What this trial tests

NA trial testing TMS in Major Depression Disorder in 55 participants. Currently enrolling.

Timeline

15 June 2025

Primary endpoint
15 December 2026

1 June 2027

Quick facts

Lead sponsor	Gulhane Training and Research Hospital
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	55
Start date	15 June 2025
Primary completion	15 December 2026
Estimated completion	1 June 2027
Sites	2 locations across Turkey (Türkiye)

Drugs / interventions tested

TMS — full drug profile →

Conditions studied

Major Depression Disorder — all drugs for Major Depression Disorder →

Sponsor

Gulhane Training and Research Hospital

Who can join

Adults 18 to 65, any sex, with Major Depression Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option for treatment-resistant depression (TRD). This study aims to identify biomarkers that predict TMS treatment response in TRD, provide insights into the neurobiological mechanisms underlying TMS efficacy, and contribute to personalized treatment strategies. By establishing proteomic and metabolomic signatures, this research seeks to enhance clinical decision-making, reduce healthcare costs, and improve patient outcomes in TRD. The findings will align with the precision medicine movement in psychiatry, advancing biomarker-driven therapeutic approaches for treatment-resistant depression.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of TMS

Trials testing the same drug.

NCT07346794 — The Underlying Neural Mechanism of TMS in Improving the Imbalance of "Microbiota-brain-gut Axis" in Alzheimer 's Disease · NA · not yet recruiting
NCT07290738 — Transcranial Magnetic Stimulation (TMS) for Negative Symptoms in Schizophrenia Spectrum Disorders · NA · recruiting
NCT07010614 — Brain Stimulation to the Hippocampus in Schizophrenia · NA · recruiting
NCT06274112 — Using TMS to Understand Neural Processes of Social Motivation · NA · recruiting
NCT07147218 — Accelerated TMS for MDD · NA · recruiting

Other recruiting trials for Major Depression Disorder

Currently open trials in the same condition.

NCT06671977 — Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans · Phase 1 · recruiting
NCT07111169 — Neuromodulation and Attention Deficits in MDD · NA · recruiting

Other Gulhane Training and Research Hospital trials

Trials by the same sponsor.

NCT07283588 — İntensive Care Sepsis Prevelance in Turkey (INSEP-TURK) · active not recruiting
NCT07145554 — f-ESWT vs Steroid Injection for Piriformis Syndrome · NA · completed
NCT06995222 — The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression in Intensive Care Clinic · recruiting
NCT06765031 — The Role of Furosemide Stress Test in the Intensive Care Clinic · NA · recruiting
NCT06601413 — Modified Thoracoabdominal Nerve Block(M-TAPA) in Total Laparoscopic Hysterectomies · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07039370 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Gulhane Training and Research Hospital
Last refreshed: 26 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07039370.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing