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NCT05039593
Oral Care Frequency in Mechanically Ventilated Patients
NA trial testing chlorhexidine in Oral Complications in 98 participants. Completed in 1 July 2022.
1 June 2022
Quick facts
| Lead sponsor | Aydin Adnan Menderes University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | sequential |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 98 |
| Start date | 5 July 2021 |
| Primary completion | 1 June 2022 |
| Estimated completion | 1 July 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- chlorhexidine (CHLORHEXIDINE) — full drug profile →
Conditions studied
- Oral Complications — all drugs for Oral Complications →
Sponsor
Aydin Adnan Menderes University
Who can join
18 and older, any sex, with Oral Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Many problems may develop in patients due to mechanical ventilation in intensive care units. These include ventilator-associated pneumonia, decreased cerebral perfusion, venous air embolism, sinus and eye infections, neuromuscular dysfunctions and skin sores may be seen in intensive care patients undergoing mechanical ventilation. If adequate oral hygiene is not provided in patients on mechanical ventilation support, dry mouth, halitosis, disruption of tissue integrity in and around the mouth, intraoral infections and periodontal diseases may occur. Most importantly, ventilator-associated pneumonia (VIP) may develop in patients dependent on mechanical ventilation due to deficient oral care. Chlorhexidine solution is widely used in oral care. However, there is a need for evidence about the frequency of oral care with which chlorhexidine solution on oral mucous membrane integrity in patients under mechanical ventilation support. Oral care frequency was not examined in these existing studies. Therefore, this study was planned to determine the effect of three different oral care frequencies on the integrity of the oral mucous membrane in patients connected to mechanical ventilators.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05039593
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
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Trials testing the same drug.
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- NCT03801187 — Surgical Protocol for Peri-implantitis Treatment · NA · unknown
- NCT03977285 — Surgical Protocol for Peri-implantitis Treatment-2 · NA · unknown
- NCT03438890 — Laparoscopic Lens Defogging Using Anti-fog Solution, waRm Saline, and Chlorhexidine Solution · NA · completed
Other Aydin Adnan Menderes University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05039593 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aydin Adnan Menderes University
- Last refreshed: 20 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05039593.
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