Last reviewed · How we verify
NCT05035628: COVID-Rehab
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
NA trial testing Cardiopulmonary exercise training in COVID-19 Respiratory Infection in 40 participants. Completed in 31 May 2023.
31 May 2023
Quick facts
| Lead sponsor | Louis Bherer |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 40 |
| Start date | 15 September 2021 |
| Primary completion | 31 May 2023 |
| Estimated completion | 31 May 2023 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Cardiopulmonary exercise training
Conditions studied
- COVID-19 Respiratory Infection — all drugs for COVID-19 Respiratory Infection →
Sponsor
Louis Bherer
Who can join
Adults 40 to 80, any sex, with COVID-19 Respiratory Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients. Quality of life, functional capacity, functional respiratory capacity, inflammatory profile, coagulation markers, cognitive functions and brain O2 saturation will also be assessed before and after the exercise rehabilitation program.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue: The COVID-Rehab Study.
Besnier F, Bérubé B, Malo J, Gagnon C, et al · · 2022 · cited 57× · PMID 35409815 · DOI 10.3390/ijerph19074133 -
Cardiopulmonary rehabilitation's influence on cognitive functions, psychological state, and sleep quality in long COVID-19 patients: A randomized controlled trial.
Gaudreau-Majeau F, Gagnon C, Djedaa SC, Bérubé B, et al · · 2025 · cited 2× · PMID 38607276 · DOI 10.1080/09602011.2024.2338613
Verify or expand the search:
- PubMed search for NCT05035628
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for COVID-19 Respiratory Infection
Currently open trials in the same condition.
- NCT06950177 — Pancoronavirus Vaccine Study in Healthy Adults · Phase 1 · active not recruiting
- NCT06402318 — Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine · recruiting
- NCT05765396 — SARS-CoV-2/COVID-19 Study of Next Generation Non-Invasive Passive Detection Technologies · active not recruiting
- NCT05689034 — Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 · Phase 2, PHASE3 · recruiting
- NCT05562505 — Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure · NA · recruiting
Other Louis Bherer trials
Trials by the same sponsor.
- NCT06130358 — Investigating the Effects of a Museum Intervention on the Psychological and Cardiac Health of Older Adults · NA · unknown
- NCT04962061 — A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors. · NA · recruiting
- NCT04635462 — The Cognitive and spOrt Virtual EPIC Training Study · NA · completed
- NCT04806841 — Effect of a Motivational Intervention on Exercise Adherence After Cardiac Rehabilitation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05035628 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Louis Bherer
- Last refreshed: 5 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05035628.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing