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NCT05034133
Durvalumab With Chemotherapy Followed by Sequential Radiotherapy for Limited Stage Small Cell Lung Cancer
Phase 2 trial testing Durvalumab in Limited Stage Small Cell Lung Cancer in 20 participants. Status unknown.
31 August 2023
Quick facts
| Lead sponsor | Beijing Haidian Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 September 2021 |
| Primary completion | 31 August 2023 |
| Estimated completion | 31 August 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Durvalumab — full drug profile →
Conditions studied
- Limited Stage Small Cell Lung Cancer — all drugs for Limited Stage Small Cell Lung Cancer →
Sponsor
Beijing Haidian Hospital
Who can join
18 and older, any sex, with Limited Stage Small Cell Lung Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single arm Phase II study, in which 6 cycles of durvalumab with chemotherapy (Etoposide and Cisplatin) and durvalumab followed by Sequential radiotherapy for limited stage small cell lung cancer.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer.
Schlick B, Shields MD, Marin-Acevedo JA, Patel I, et al · · 2022 · cited 12× · PMID 35716328 · DOI 10.1007/s11864-022-00989-7 -
State of the art in treatment of small cell lung cancer.
Behrouzi R, Blackhall F. · · 2025 · cited 1× · PMID 40964483 · DOI 10.1177/17588359251363518
Verify or expand the search:
- PubMed search for NCT05034133
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Durvalumab
Trials testing the same drug.
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- NCT07339059 — Phase II Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Ce · Phase 2 · recruiting
- NCT07531095 — Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC) · Phase 1 · not yet recruiting
- NCT07459634 — A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC · Phase 2 · not yet recruiting
Other recruiting trials for Limited Stage Small Cell Lung Cancer
Currently open trials in the same condition.
- NCT06943235 — Study of Probiotics Combined With Concurrent Hyperfractionated ChemoRadiotherapy and Adebrelimab Immunomaintenance in th · Phase 2 · recruiting
- NCT06256237 — Neoadjuvant Therapy With Toripalimab and JS004 Combined With Etoposide and Platinum Chemotherapy for Limited-stage Small · Phase 2 · recruiting
- NCT06117774 — Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC) · Phase 3 · recruiting
- NCT05623267 — Sugemalimab as Consolidation Therapy in Patients With LS-SCLC Following cCRT or sCRT · Phase 2, PHASE3 · recruiting
- NCT05443646 — Consolidation Serplulimab Following Concurrent Chemoradiotherapy for LS-SCLC Patients · Phase 2 · recruiting
Other Beijing Haidian Hospital trials
Trials by the same sponsor.
- NCT07257471 — Application Research of Methylation Markers in Early-stage Lung Cancer Patients Treated With Co-ablation System Therapy · recruiting
- NCT07257458 — Application of Methylation Markers in Early Detection and MRD Monitoring of Lung Cancer · recruiting
- NCT06973499 — Exploratory Study of the Microbiome of Upper Gastrointestinal in the Pathogenesis of Multiple Primary Lung Cancer · completed
- NCT03098914 — Clinical Characteristics and Microbiology of Community-Acquired Pneumonia · unknown
- NCT03170830 — Diagnostic Value of CircRNA-Uck2 for Acute Myocardial Infarction · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05034133 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Haidian Hospital
- Last refreshed: 5 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05034133.
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