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NCT03170830
Diagnostic Value of CircRNA-Uck2 for Acute Myocardial Infarction
NA trial testing the diagnosis value of cUck2 in acute myocardial infarction. in Cardiac Disease in 178 participants. Status unknown.
31 December 2018
Quick facts
| Lead sponsor | Beijing Haidian Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 178 |
| Start date | 1 August 2015 |
| Primary completion | 31 December 2018 |
| Estimated completion | 31 December 2018 |
| Sites | 1 location across China |
Drugs / interventions tested
- the diagnosis value of cUck2 in acute myocardial infarction.
Conditions studied
- Cardiac Disease — all drugs for Cardiac Disease →
- Diagnoses Disease — all drugs for Diagnoses Disease →
- Acute Myocardial Infarction — all drugs for Acute Myocardial Infarction →
Sponsor
Beijing Haidian Hospital
Who can join
18 and older, any sex, with Cardiac Disease or Diagnoses Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an observational diagnostic study that aims to evaluate the diagnostic value of circRNA-Uck2 in Acute Myocardial Infarction (AMI) in adults as compared to healthy and unstable angina controls. Rapid and adequate diagnosis of AMI is of great importance to enable a rapid start of treatment, save large tracts of dying myocardium, reduce the infarct size,and thereby decrease the risk of subsequent heart failure.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Roles of circular RNA in breast cancer: present and future.
Li Z, Chen Z, Hu G, Jiang Y. · · 2019 · cited 76× · PMID 31396311 -
The emerging role and significance of circular RNAs in viral infections and antiviral immune responses: possible implication as theranostic agents.
Awan FM, Yang BB, Naz A, Hanif A, et al · · 2021 · cited 53× · PMID 32615049 · DOI 10.1080/15476286.2020.1790198 -
A Dual-Circular RNA Signature as a Non-invasive Diagnostic Biomarker for Gastric Cancer.
Han L, Zhang X, Wang A, Ji Y, et al · · 2020 · cited 18× · PMID 32154178 · DOI 10.3389/fonc.2020.00184 -
Noncoding RNAs as Promising Diagnostic Biomarkers and Therapeutic Targets in Intestinal Fibrosis of Crohn's Disease: The Path From Bench to Bedside.
Zhou LY, Lin SN, Rieder F, Chen MH, et al · · 2021 · cited 11× · PMID 33324986 · DOI 10.1093/ibd/izaa321 -
Circular RNAs in the Origin of Developmental Lung Disease: Promising Diagnostic and Therapeutic Biomarkers.
Tong Y, Zhang S, Riddle S, Song R, et al · · 2023 · cited 8× · PMID 36979468 · DOI 10.3390/biom13030533 -
Hints From the Cellular Functions to the Practical Outlook of Circular RNAs.
Yesharim L, Mojbafan M, Abiri M. · · 2021 · cited 7× · PMID 34220952 · DOI 10.3389/fgene.2021.679446 -
Circular RNAs in Cardiovascular Physiopathology: From Molecular Mechanisms to Therapeutic Opportunities.
Capirossi G, Brasini S, Tremoli E, Binatti A, et al · · 2025 · cited 1× · PMID 41096990 · DOI 10.3390/ijms26199725 -
Decoding the regulatory roles of circular RNAs in cardiac fibrosis.
You Q, Yu J, Pan R, Feng J, et al · · 2025 · cited 1× · PMID 39759175 · DOI 10.1016/j.ncrna.2024.11.007
Verify or expand the search:
- PubMed search for NCT03170830
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03170830 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Haidian Hospital
- Last refreshed: 31 May 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03170830.
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