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NCT05023057: SUPERBRAIN
Multidomain Interventions Via Face-to-face and Video Communication Platforms in Mild Cognitive Impairment
NA trial testing Multidomain intervention in Mild Cognitive Impairment in 300 participants. Completed in 22 March 2023.
22 March 2023
Quick facts
| Lead sponsor | Inha University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 300 |
| Start date | 23 September 2021 |
| Primary completion | 22 March 2023 |
| Estimated completion | 22 March 2023 |
| Sites | 17 locations across South Korea |
Drugs / interventions tested
- Multidomain intervention
Conditions studied
- Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →
Sponsor
Inha University Hospital
Who can join
Adults 60 to 85, any sex, with Mild Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will be done to investigate the effectiveness of a 24-week multidomain intervention program consisting of cognitive training, exercise, nutrition management, vascular disease risk factor management, social activity, and motivational enhancement on the cognitive function compared to the control group in mild cognitive impairment.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
South Korean study to prevent cognitive impairment and protect brain health through multidomain interventions via face-to-face and video communication platforms in mild cognitive impairment (SUPERBRAIN-MEET): A randomized controlled trial.
Moon SY, Park YK, Jeong JH, Hong CH, et al · · 2025 · cited 18× · PMID 39840755 · DOI 10.1002/alz.14517 -
SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN health through Multidomain interventions via facE-to-facE and video communication plaTforms in mild cognitive impairment (SUPERBRAIN-MEET): Protocol for a Multicenter Randomized Controlled Trial.
Cho SH, Kang HJ, Park YK, Moon SY, et al · · 2024 · cited 6× · PMID 38362052 · DOI 10.12779/dnd.2024.23.1.30 -
Developing digital biomarker for predicting cognitive response to multi-domain intervention.
Park JH, Kim HS, Choi SH, Jeong JH, et al · · 2026 · PMID 41617781 · DOI 10.1038/s41598-026-37123-8 -
Polygenicity and APOE ε4 shape response to intervention in mild cognitive impairment.
Hwang J, Moon SY, Lee H, Lee J, et al · · 2025 · PMID 41388319 · DOI 10.1186/s13195-025-01907-3
Verify or expand the search:
- PubMed search for NCT05023057
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials testing the same drug.
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Other recruiting trials for Mild Cognitive Impairment
Currently open trials in the same condition.
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- NCT07220694 — Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairmen · NA · recruiting
- NCT06983769 — CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial · NA · recruiting
- NCT07318038 — The Use of Rhythmic Light Therapy in Mild Cognitive Impairment · NA · recruiting
Other Inha University Hospital trials
Trials by the same sponsor.
- NCT07306520 — Effects of the Health Promotion Program on Health Literacy, Physical and Mental Health Status, and Quality of Life · NA · active not recruiting
- NCT05659420 — High Intensity Interval Training in Chronic Heart Failure · NA · unknown
- NCT06573268 — Da-vinci sp Versus xi Thyroid Surgery · completed
- NCT05873023 — Chewing Gum and Cognitive Function · NA · unknown
- NCT06963372 — Assessment of Health Effects of Air Purifier Interventions on Chronic Kidney Disease Patients · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05023057 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Inha University Hospital
- Last refreshed: 4 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05023057.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing