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NCT05023057: SUPERBRAIN

Multidomain Interventions Via Face-to-face and Video Communication Platforms in Mild Cognitive Impairment

Completed NA Last updated 4 December 2024
What this trial tests

NA trial testing Multidomain intervention in Mild Cognitive Impairment in 300 participants. Completed in 22 March 2023.

Timeline
23 September 2021
Primary endpoint
22 March 2023
22 March 2023

Quick facts

Lead sponsorInha University Hospital
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeprevention
Enrollment300
Start date23 September 2021
Primary completion22 March 2023
Estimated completion22 March 2023
Sites17 locations across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Inha University Hospital

Who can join

Adults 60 to 85, any sex, with Mild Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will be done to investigate the effectiveness of a 24-week multidomain intervention program consisting of cognitive training, exercise, nutrition management, vascular disease risk factor management, social activity, and motivational enhancement on the cognitive function compared to the control group in mild cognitive impairment.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. South Korean study to prevent cognitive impairment and protect brain health through multidomain interventions via face-to-face and video communication platforms in mild cognitive impairment (SUPERBRAIN-MEET): A randomized controlled trial.
    Moon SY, Park YK, Jeong JH, Hong CH, et al · · 2025 · cited 18× · PMID 39840755 · DOI 10.1002/alz.14517
  2. SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN health through Multidomain interventions via facE-to-facE and video communication plaTforms in mild cognitive impairment (SUPERBRAIN-MEET): Protocol for a Multicenter Randomized Controlled Trial.
    Cho SH, Kang HJ, Park YK, Moon SY, et al · · 2024 · cited 6× · PMID 38362052 · DOI 10.12779/dnd.2024.23.1.30
  3. Developing digital biomarker for predicting cognitive response to multi-domain intervention.
    Park JH, Kim HS, Choi SH, Jeong JH, et al · · 2026 · PMID 41617781 · DOI 10.1038/s41598-026-37123-8
  4. Polygenicity and APOE ε4 shape response to intervention in mild cognitive impairment.
    Hwang J, Moon SY, Lee H, Lee J, et al · · 2025 · PMID 41388319 · DOI 10.1186/s13195-025-01907-3

Verify or expand the search:

Other trials of Multidomain intervention

Trials testing the same drug.

Other recruiting trials for Mild Cognitive Impairment

Currently open trials in the same condition.

Other Inha University Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05023057.

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