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NCT03056768: THISCE
Taiwan Health Promotion Intervention Study for Elders
NA trial testing Multidomain intervention in Frail Elderly Syndrome in 1,080 participants. Completed in 24 July 2016.
5 October 2015
Quick facts
| Lead sponsor | Taipei Veterans General Hospital, Taiwan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 1,080 |
| Start date | 30 August 2014 |
| Primary completion | 5 October 2015 |
| Estimated completion | 24 July 2016 |
Drugs / interventions tested
- Multidomain intervention
- Active control — full drug profile →
Conditions studied
- Frail Elderly Syndrome — all drugs for Frail Elderly Syndrome →
- Cognitive Impairment — all drugs for Cognitive Impairment →
- Cognitive Decline — all drugs for Cognitive Decline →
Sponsor
Taipei Veterans General Hospital, Taiwan
Who can join
65 and older, any sex, with Frail Elderly Syndrome or Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objectives: 1-year multidomain health promotion on prevention of physical and cognitive decline for community-living older people. Design: Methods: Randomized controlled trial Setting: Five cities(Taipei, Taichung, Kaohsiung, Kinmen, I-Lan) in Taiwan Participants: age 65 or older community-dwelling prefrail or frail adults Intervention: 1-year multidomain health promotion (physical, cognitive, nutritional intervention) Measurements: Primary outcome includes frailty status and cognitive performance. Secondary outcomes include depressive symptoms, nutrition assessment, and functional capacity; All the variables were measured at 0, 6, 12 months. The effect of intervention was investigated by intention-to-treat analysis.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Efficacy of multidomain interventions to improve physical frailty, depression and cognition: data from cluster-randomized controlled trials.
Chen LK, Hwang AC, Lee WJ, Peng LN, et al · · 2020 · cited 90× · PMID 32134208 · DOI 10.1002/jcsm.12534 -
Tailoring multidomain intervention programs to reduce cognitive and physical decline in older adults: Examining rural-urban differences in a nationwide cluster-randomized controlled trial.
Ho MY, Lee WJ, Yen KH, Liang CK, et al · · 2025 · cited 1× · PMID 40514302 · DOI 10.1016/j.tjpad.2025.100231
Verify or expand the search:
- PubMed search for NCT03056768
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT05023057 — Multidomain Interventions Via Face-to-face and Video Communication Platforms in Mild Cognitive Impairment · NA · completed
- NCT03095820 — Multidomain Intervention for Older Adults With Major Depressive Disorder · NA · completed
Other recruiting trials for Frail Elderly Syndrome
Currently open trials in the same condition.
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- NCT06444321 — INTEgRated Health CARE for Patients With Frailty and Heart Failure · NA · recruiting
- NCT05993754 — Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams · NA · recruiting
- NCT06496022 — Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome · active not recruiting
Other Taipei Veterans General Hospital, Taiwan trials
Trials by the same sponsor.
- NCT07463443 — Effectiveness of Chatbot for Improving Caregiving Outcomes in Primary Caregivers of Geriatric Pneumonia Patients: A Stud · NA · not yet recruiting
- NCT07400757 — Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease · NA · not yet recruiting
- NCT07362134 — Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter · NA · enrolling by invitation
- NCT07473687 — Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room · recruiting
- NCT07344207 — GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03056768 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Veterans General Hospital, Taiwan
- Last refreshed: 17 February 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03056768.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing