Who is sponsoring NCT05019222?

NCT05019222 is sponsored by Gangnam Severance Hospital.

What drugs are being tested in NCT05019222?

Interventions in NCT05019222: Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia.

What condition does NCT05019222 study?

NCT05019222 studies Anterior Cervical Discectomy and Fusion (ACDF) Surgery.

Is NCT05019222 still recruiting?

NCT05019222 is currently completed. Last updated 25 April 2023.

Last reviewed 2023-04-25 · How we verify

NCT05019222

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam

Completed NA Last updated 25 April 2023

What this trial tests

NA trial testing Sevoflurane based inhalation anesthesia in Anterior Cervical Discectomy and Fusion (ACDF) Surgery in 72 participants. Completed in 14 August 2022.

Timeline

26 September 2021

Primary endpoint
14 August 2022

14 August 2022

Quick facts

Lead sponsor	Gangnam Severance Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	other
Enrollment	72
Start date	26 September 2021
Primary completion	14 August 2022
Estimated completion	14 August 2022
Sites	1 location across South Korea

Drugs / interventions tested

Sevoflurane based inhalation anesthesia — full drug profile →
Remimazolam based total intravenous anesthesia — full drug profile →

Conditions studied

Anterior Cervical Discectomy and Fusion (ACDF) Surgery — all drugs for Anterior Cervical Discectomy and Fusion (ACDF) Surgery →

Sponsor

Gangnam Severance Hospital

Who can join

Adults 20 to 70, any sex, with Anterior Cervical Discectomy and Fusion (ACDF) Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperative nausea/vomiting and malignant hyperthermia. However, it is still not enough to explain which is better between TIVA or inhalation anesthesia. In particular, there is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA with remimazolam. The hypothesis of the investigators study is that, in patients with cervical spine surgery, total intravenous anesthesia based on remimazolam can improve the the quality of recovery compared to inhalation anesthesia based on sevoflurane.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparison of Remimazolam versus Sevoflurane on the Postoperative Quality of Recovery in Cervical Spine Surgery: A Prospective Randomized Controlled Double-Blind Trial.
Lee J, Han DW, Kim NY, Kim KS, et al · · 2024 · cited 11× · PMID 38283136 · DOI 10.2147/dddt.s441622

Verify or expand the search:

Other Gangnam Severance Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05019222 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Gangnam Severance Hospital
Last refreshed: 25 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05019222.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing