NCT05002101 (RCTZ) is a Phase 4 clinical trial of zinc in Zinc Deficiency, sponsored by Ain Shams University.

Who is sponsoring NCT05002101?

NCT05002101 is sponsored by Ain Shams University.

What drugs are being tested in NCT05002101?

Interventions in NCT05002101: zinc, Placebo.

What condition does NCT05002101 study?

NCT05002101 studies Zinc Deficiency, Child Nutrition Disorders.

Is NCT05002101 still recruiting?

NCT05002101 is currently completed. Last updated 12 August 2021.

Last reviewed 2021-08-12 · How we verify

NCT05002101: RCTZ

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Daily Zinc Supplement Effect on Prevention of Diarrhea and Acute Respiratory Infections in Children Less Than Five Years

Completed Phase 4 Last updated 12 August 2021

What this trial tests

Phase 4 trial testing zinc in Zinc Deficiency in 140 participants. Completed in 1 August 2020.

Timeline

1 August 2018

Primary endpoint
1 August 2019

1 August 2020

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	140
Start date	1 August 2018
Primary completion	1 August 2019
Estimated completion	1 August 2020
Sites	1 location across Egypt

Drugs / interventions tested

zinc — full drug profile →
Placebo

Conditions studied

Zinc Deficiency — all drugs for Zinc Deficiency →
Child Nutrition Disorders — all drugs for Child Nutrition Disorders →

Sponsor

Ain Shams University

Who can join

Adults 6 Months to 5, any sex, with Zinc Deficiency or Child Nutrition Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Zinc deficiency in children is a major problem which leads to compromised immunity and accordingly repeated infections. This study aims to investigate the effect of supplementing zinc to decrease the incidence of diarrhea and respiratory illness in children between 6 months and 5 years in Paediatric Outpatient Clinic in Ain Shams University Hospital.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Zinc for prevention and treatment of the common cold.
Nault D, Machingo TA, Shipper AG, Antiporta DA, et al · · 2024 · cited 7× · PMID 38719213 · DOI 10.1002/14651858.cd014914.pub2
Effect of Zinc Supplementation in Children Less Than 5 Years on Diarrhea Attacks: A Randomized Controlled Trial.
Abd El-Ghaffar YS, Shouman AE, Hakim SA, El Gendy YGA, et al · · 2022 · cited 7× · PMID 35747897 · DOI 10.1177/2333794x221099266

Verify or expand the search:

Other trials of zinc

Trials testing the same drug.

NCT05156684 — Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia · NA · unknown
NCT04447534 — Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 · Phase 3 · completed

Other recruiting trials for Zinc Deficiency

Currently open trials in the same condition.

NCT06219525 — Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants · NA · recruiting
NCT05236374 — Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc · NA · recruiting
NCT04694235 — Egg Intervention During Pregnancy in Indonesia · NA · active not recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05002101 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 12 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05002101.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing