NCT04994158 (MASCOT-R) is a clinical trial of Drugs, procedures in Myeloproliferative Neoplasm, sponsored by Royal Free Hospital NHS Foundation Trust.

Who is sponsoring NCT04994158?

NCT04994158 is sponsored by Royal Free Hospital NHS Foundation Trust.

What drugs are being tested in NCT04994158?

Interventions in NCT04994158: Drugs, procedures.

What condition does NCT04994158 study?

NCT04994158 studies Myeloproliferative Neoplasm, Splanchnic Vein Thrombosis, JAK2 V617.

Is NCT04994158 still recruiting?

NCT04994158 is currently completed. Last updated 30 July 2025.

Last reviewed 2025-07-30 · How we verify

NCT04994158: MASCOT-R

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MASCOT Registry of Patients With Myeloproliferative Neoplasms Associated Splanchnic Vein Thrombosis

Completed Last updated 30 July 2025

What this trial tests

trial testing Drugs, procedures in Myeloproliferative Neoplasm in 238 participants. Completed in 21 September 2023.

Timeline

1 September 2019

Primary endpoint
21 September 2023

21 September 2023

Quick facts

Lead sponsor	Royal Free Hospital NHS Foundation Trust
Status	Completed
Study type	OBSERVATIONAL
Enrollment	238
Start date	1 September 2019
Primary completion	21 September 2023
Estimated completion	21 September 2023
Sites	1 location across United Kingdom

Drugs / interventions tested

Drugs, procedures

Conditions studied

Myeloproliferative Neoplasm — all drugs for Myeloproliferative Neoplasm →
Splanchnic Vein Thrombosis — all drugs for Splanchnic Vein Thrombosis →
JAK2 V617 — all drugs for JAK2 V617 →

Sponsor

Royal Free Hospital NHS Foundation Trust

Who can join

18 and older, any sex, with Myeloproliferative Neoplasm or Splanchnic Vein Thrombosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A registry of UK patients diagnosed to have splanchnic vein thrombosis and myeloproliferative neoplasm, including isolated mutation of JAK2V617f. The purpose of the registry is to understand outcomes, treatment variations and data to inform and enable future clinical trial design and facilitate regulatory approval decision-making.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Myeloproliferative Neoplasm

Currently open trials in the same condition.

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Other Royal Free Hospital NHS Foundation Trust trials

Trials by the same sponsor.

NCT06484478 — A Real-world Wearables Study in Fabry Disease. · completed
NCT06084052 — Path Active Multicentre Randomised Controlled Trial (Previous Pilot: Path Active; Safety and Tolerability Study) · NA · recruiting
NCT07392710 — Clinical Evaluation of the Nova Max Pro StatSensor Device · NA · completed
NCT05167201 — Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom · NA · unknown
NCT05189600 — Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04994158 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Royal Free Hospital NHS Foundation Trust
Last refreshed: 30 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04994158.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing