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NCT04989868
Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula
NA trial testing Trans-Nasal Afferent Loop Decompression in Pancreatic Fistula in 299 participants. Completed in 12 November 2022.
12 November 2022
Quick facts
| Lead sponsor | The First Affiliated Hospital with Nanjing Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 299 |
| Start date | 6 August 2021 |
| Primary completion | 12 November 2022 |
| Estimated completion | 12 November 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- Trans-Nasal Afferent Loop Decompression
- Without Trans-Nasal Afferent Loop Decompression
Conditions studied
- Pancreatic Fistula — all drugs for Pancreatic Fistula →
- Pancreaticoduodenectomy — all drugs for Pancreaticoduodenectomy →
- Complication of Surgical Procedure — all drugs for Complication of Surgical Procedure →
Sponsor
The First Affiliated Hospital with Nanjing Medical University
Who can join
Adults 18 to 85, any sex, with Pancreatic Fistula or Pancreaticoduodenectomy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD). Trans-nasal afferent loop decompression technique (TNALD) may reduce the rate of POPF based on our previous retrospective study. The aim of this open-label randomized controlled trial is to determine whether TNALD is a protective factor against the development of POPF after PD.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04989868
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pancreatic Fistula
Currently open trials in the same condition.
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Other The First Affiliated Hospital with Nanjing Medical University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04989868 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
- Last refreshed: 8 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04989868.
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