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NCT04987164
Incidence of Cystitis in Women Consuming a Mixture of Cranberry, Cinnamon, Probiotics
trial testing Feminabiane CBU in Cystitis in 80 participants. Completed in 4 August 2022.
4 August 2022
Quick facts
| Lead sponsor | CEN Biotech |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 18 November 2021 |
| Primary completion | 4 August 2022 |
| Estimated completion | 4 August 2022 |
| Sites | 2 locations across France |
Drugs / interventions tested
- Feminabiane CBU
Conditions studied
- Cystitis — all drugs for Cystitis →
- Urinary Tract Infections — all drugs for Urinary Tract Infections →
Sponsor
CEN Biotech — full company profile →
Who can join
Adults 18 to 65, female only, with Cystitis or Urinary Tract Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cranberries are traditionally used for urinary comfort and prevention of urinary disorders of bacterial origin and despite an EFSA opinion invalidating the clinical efficacy of cranberries, its mechanism of action has been several times proposed by the scientific community: it would act by inhibiting the synthesis of P-fimbriae leading to a complete disappearance of these adhesins, and to bacterial-type deformation by lengthening of the cell body. Cinnamon and microbiotic strains could enhance this synergy. This study aims to evaluate the effectiveness of a food supplement based on cranberry, cinnamon and microbiotic strains (Feminabiane CBU) on the symptoms of cystitis, urinary discomfort and the number of cystitis reported by women.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of a supplement associating <i>Lactobacillus</i> strains and proanthocyanidin-rich plant extracts against recurrent uncomplicated, urinary tract infections: A prospective, controlled study.
Ait Abdellah S, Leblanc A, Dauchet Q, Blondeau C, et al · · 2025 · PMID 39791583 · DOI 10.4111/icu.20240092
Verify or expand the search:
- PubMed search for NCT04987164
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04987164 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by CEN Biotech
- Last refreshed: 2 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04987164.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing