Last reviewed · How we verify
NCT06617975: SANTIAGO
Knee Osteoarthritis and Spa Therapy
NA trial testing Balneotherapy program in rheumatology indication in Knee Osteoarthritis in 80 participants. Currently enrolling.
15 December 2026
Quick facts
| Lead sponsor | CEN Biotech |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 80 |
| Start date | 14 October 2024 |
| Primary completion | 15 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across France |
Drugs / interventions tested
- Balneotherapy program in rheumatology indication
Conditions studied
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Knee Osteoarthritis (OA) — all drugs for Knee Osteoarthritis (OA) →
Sponsor
CEN Biotech — full company profile →
Who can join
Adults 50 to 80, any sex, with Knee Osteoarthritis or Knee Osteoarthritis (OA). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this clinical trial is to assess the efficacy of the 18-day balneotherapy program (therapeutic indication: Rheumatology) in terms of functional incapacity and the disorders (pain, joint stiffness) induced by osteoarthritis of the knee, and thus improves patients\' quality of life, in patients presented with knee osteoarthritis. The French National Academy of Medicine encourages the re-use of RCT data when available. In this context, the current study is designed as a single-arm prospective study with external comparison using the propensity score. The Control group consists of the patients which were allocated to the Control group of reference randomized clinical trial (RCT) "ANGELLO Study" (NCT05819437). These patients received standard care for knee osteoarthritis, i.e., pain management and exercise recommendations. All patients enrolled in the current study benefit of 18-day balneotherapy program (therapeutic indication: Rheumatology) with Mineral Water of Santenay (Burgundy, France), and examination with a practitioner at enrollment and 6 months after the beginning of spa treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06617975
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Knee Osteoarthritis
Currently open trials in the same condition.
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- NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
- NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting
Other CEN Biotech trials
Trials by the same sponsor.
- NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
- NCT07295678 — URGO FilmoCream Eczema + Dermocorticoids in Atopic Dermatitis · NA · not yet recruiting
- NCT06278324 — Effectiveness of a Nasal Spray on Viral Respiratory Infections · NA · completed
- NCT06054737 — Chronic Venous Insufficiency and Balneotherapy · completed
- NCT06186375 — Performance of PEAR 2.0 Software in Prescribing Biotherapy in Patients With Rheumatoid Arthritis · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06617975 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by CEN Biotech
- Last refreshed: 7 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06617975.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing