Who is sponsoring NCT04985838?

NCT04985838 is sponsored by Glasgow Caledonian University.

What drugs are being tested in NCT04985838?

Interventions in NCT04985838: HEADS: UP (Helping Ease Anxiety and Depression).

Is NCT04985838 still recruiting?

NCT04985838 is currently completed. Last updated 28 March 2023.

Last reviewed 2023-03-28 · How we verify

NCT04985838: HEADS:UP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Helping Ease Anxiety and Depression Following Stroke Stage 3

Completed NA Last updated 28 March 2023

What this trial tests

NA trial testing HEADS: UP (Helping Ease Anxiety and Depression) in Stroke in 64 participants. Completed in 1 September 2022.

Timeline

28 June 2021

Primary endpoint
1 September 2022

1 September 2022

Quick facts

Lead sponsor	Glasgow Caledonian University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	64
Start date	28 June 2021
Primary completion	1 September 2022
Estimated completion	1 September 2022
Sites	1 location across United Kingdom

Drugs / interventions tested

HEADS: UP (Helping Ease Anxiety and Depression)

Conditions studied

Stroke — all drugs for Stroke →
Cerebrovascular Accident Due to Cerebral Artery Occlusion — all drugs for Cerebrovascular Accident Due to Cerebral Artery Occlusion →
Anxiety — all drugs for Anxiety →
Depression — all drugs for Depression →

Sponsor

Glasgow Caledonian University

Who can join

18 and older, any sex, with Stroke or Cerebrovascular Accident Due to Cerebral Artery Occlusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A mixed methods randomised controlled pilot trial, conducted in miniature of future definitive trial, in which the investigators will test optimised intervention and study processes. The investigators will individually randomise stroke survivor participants in a 1:1 allocation to: HEADS: UP or Control.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Pharmacological, non-invasive brain stimulation and psychological interventions, and their combination, for treating depression after stroke.
Allida SM, Hsieh CF, Cox KL, Patel K, et al · · 2023 · cited 11× · PMID 37417452 · DOI 10.1002/14651858.cd003437.pub5
Meditation for the primary and secondary prevention of cardiovascular disease.
Rees K, Takeda A, Court R, Kudrna L, et al · · 2024 · cited 5× · PMID 38358047 · DOI 10.1002/14651858.cd013358.pub2
The HEADS: UP Development Study: Working with Key Stakeholders to Adapt a Mindfulness-Based Stress Reduction Course for People with Anxiety and Depression after Stroke.
Lawrence M, Davis B, De Amicis L, Booth J, et al · · 2023 · cited 5× · PMID 36766930 · DOI 10.3390/healthcare11030355
ESOC 2023 Abstract Book
· 2023

Verify or expand the search:

Other recruiting trials for Stroke

Currently open trials in the same condition.

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NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other Glasgow Caledonian University trials

Trials by the same sponsor.

NCT07500077 — Strength and Balance Integration in Maintenance Cardiac Rehabilitation for Older Adults · NA · recruiting
NCT06884709 — Activity-based Mirror Therapy for Lower Limb Motor Recovery, Balance, Gait, and Mobility in Acute Inpatient Stroke: A Fe · NA · not yet recruiting
NCT07385456 — FES Arm Cycling on Functional Ability and Strength in People With SCI · NA · completed
NCT06154122 — Virtual Reality Upper Limb Therapy for People With Spinal Cord Injury · NA · completed
NCT06114732 — Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudicat · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04985838 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Glasgow Caledonian University
Last refreshed: 28 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04985838.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing