NCT04981639 is a Phase 3 clinical trial of IVPCA in Cytoreductive Surgery, sponsored by Gangnam Severance Hospital.

Who is sponsoring NCT04981639?

NCT04981639 is sponsored by Gangnam Severance Hospital.

What drugs are being tested in NCT04981639?

Interventions in NCT04981639: IVPCA, TAP, IMS.

What condition does NCT04981639 study?

NCT04981639 studies Cytoreductive Surgery.

Is NCT04981639 still recruiting?

NCT04981639 is currently completed. Last updated 10 October 2022.

Last reviewed 2022-10-10 · How we verify

NCT04981639

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TAP and IMS for HIPEC

Completed Phase 3 Last updated 10 October 2022

What this trial tests

Phase 3 trial testing IVPCA in Cytoreductive Surgery in 81 participants. Completed in 14 June 2022.

Timeline

21 August 2021

Primary endpoint
14 June 2022

14 June 2022

Quick facts

Lead sponsor	Gangnam Severance Hospital
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	81
Start date	21 August 2021
Primary completion	14 June 2022
Estimated completion	14 June 2022
Sites	1 location across South Korea

Drugs / interventions tested

IVPCA — full drug profile →
TAP
IMS

Conditions studied

Cytoreductive Surgery — all drugs for Cytoreductive Surgery →

Sponsor

Gangnam Severance Hospital

Who can join

19 and older, any sex, with Cytoreductive Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is important to decrease the postoperative pain in patients undergoing cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy. We will compare the Transversus abdominis plane block with the Transversus abdominis plane block plus intramuscular electrical stimulation in patients undergoing cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Current Research and Development in Hyperthermic Intraperitoneal Chemotherapy (HIPEC)-A Cross-Sectional Analysis of Clinical Trials Registered on ClinicalTrials.gov.
Ukegjini K, Guidi M, Lehmann K, Süveg K, et al · · 2023 · cited 7× · PMID 37046587 · DOI 10.3390/cancers15071926
Analgesic effects of combined transversus abdominis plane block and intramuscular electrical stimulation in patients undergoing cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy: a randomized controlled trial.
Kim HC, Park J, Oh J, Oh J, et al · · 2023 · cited 2× · PMID 36999805 · DOI 10.1097/js9.0000000000000383

Verify or expand the search:

Other trials of IVPCA

Trials testing the same drug.

NCT03878082 — Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain · NA · completed

Other recruiting trials for Cytoreductive Surgery

Currently open trials in the same condition.

NCT05597683 — Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy · NA · recruiting
NCT05316181 — CRS & HIPEC for Platinum-Resistant Recurrent Ovarian Cancer (KOV-02R, RECOVER) · Phase 3 · active not recruiting

Other Gangnam Severance Hospital trials

Trials by the same sponsor.

NCT07505628 — AI-based Rehabilitation for Hip and Knee Surgery Patients · NA · not yet recruiting
NCT07311122 — Endocrine Therapy Base on 21-gene RS · not yet recruiting
NCT07011823 — Immune-checkpoint Blockade After Partial Breast Irradiation by Pembrolizumab in Early TNBC · Phase 2 · not yet recruiting
NCT07211451 — Axillary Nodal Burden in HER2+ and TNBC · completed
NCT06839716 — Comparison of Ropivacaine-Poloxamer 407 Hydrogel and TAP Block for Postoperative Pain Management in Laparoscopic/Robotic · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04981639 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Gangnam Severance Hospital
Last refreshed: 10 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04981639.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing