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NCT04981301
Quadratus Lumborum Block for Lumbar Spinal Surgery
NA trial testing Quadratus Lumborum Block in Lumbar Disc Herniation in 60 participants. Completed in 1 January 2022.
30 December 2021
Quick facts
| Lead sponsor | Medipol University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 2 August 2021 |
| Primary completion | 30 December 2021 |
| Estimated completion | 1 January 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Quadratus Lumborum Block — full drug profile →
Conditions studied
- Lumbar Disc Herniation — all drugs for Lumbar Disc Herniation →
Sponsor
Medipol University
Who can join
Adults 18 to 65, any sex, with Lumbar Disc Herniation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Spine surgery in thoracolumbar region is one of the most common surgeries performed for the treatment of leg and back pain. Pain management is especially important for these patients since chronic pain often occurs after surgery. Severe pain may occur at postoperative period in patients following lumbar disc herniation (LDH) operation. Postoperative effective pain treatment provides early mobilization and shorter hospital stay, thus complications due to hospitalization such as infection and thromboembolism may be reduced. Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves. The aim of this study is to evaluate the efficacy of US-guided QLB for postoperative analgesia management after lumbar disc herniation-laminectomy surgery. The primary aim is to evaluate postoperative pain scores (VAS), the secondary aim is to evaluate use of rescue analgesia and adverse effects (allergic reaction, nausea, vomiting).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The efficacy of ultrasound-guided anterior quadratus lumborum block for pain management following lumbar spinal surgery: a randomized controlled trial.
Alver S, Bahadir C, Tahta AC, Cetinkal A, et al · · 2022 · cited 12× · PMID 36536307 · DOI 10.1186/s12871-022-01943-8
Verify or expand the search:
- PubMed search for NCT04981301
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Quadratus Lumborum Block
Trials testing the same drug.
- NCT07256535 — Blood Bupivacaine Concentration After Regional Block Applications in Pediatric Patients · NA · not yet recruiting
- NCT07094386 — Postoperative Analgesia in Patients Undergoing Open Upper Abdominal Surgeries: External Oblique Intercostal Plane Block · NA · recruiting
- NCT07166250 — Comparison of the Effects of Quadratus Lumborum Block and Retrolaminar Block on Postoperative Pain in Lumbar Disc Hernia · NA · active not recruiting
- NCT05217121 — QLB vs mTLIP for Lumbar Spinal Surgery · NA · completed
- NCT04074226 — ESP vs QL for Total Abdominal Hysterectomy · NA · terminated
Other recruiting trials for Lumbar Disc Herniation
Currently open trials in the same condition.
- NCT07349719 — Dynamic Compliance-Guided Ventilation in Lumbar Surgery · NA · recruiting
- NCT07293676 — IASTM and Vibration Effects on Pain, Functionality, and Kinesiophobia in Lumbar Disc Herniation · NA · recruiting
- NCT07184554 — Lumbar Disc Hernia, Erector Spinae Plane Block, Ilesi · NA · recruiting
- NCT06853132 — Baduanjin With Resistance Training Program · NA · recruiting
- NCT07085247 — The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease · recruiting
Other Medipol University trials
Trials by the same sponsor.
- NCT07277803 — Device-Based vs Manual Sensory Training in Low Back Pain · NA · not yet recruiting
- NCT07214636 — Development and Investigation of the ApneaTheraPlay · NA · not yet recruiting
- NCT07534475 — Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT · NA · not yet recruiting
- NCT07534488 — Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery · NA · not yet recruiting
- NCT07525648 — Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04981301 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medipol University
- Last refreshed: 11 February 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04981301.
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