Who is sponsoring NCT04966858?

NCT04966858 is sponsored by University of California, San Francisco.

What drugs are being tested in NCT04966858?

Interventions in NCT04966858: Individualized Caloric Refeeding (ICR), Higher Calorie Refeeding (HCR).

What condition does NCT04966858 study?

NCT04966858 studies Atypical Anorexia Nervosa.

Is NCT04966858 still recruiting?

NCT04966858 is currently enrolling by invitation. Last updated 23 January 2026.

Last reviewed 2026-01-23 · How we verify

NCT04966858: i-STRONG

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Individualized Study of Refeeding to Optimize iNpatient Gains

ENROLLING BY INVITATION NA Last updated 23 January 2026

What this trial tests

NA trial testing Individualized Caloric Refeeding (ICR) in Atypical Anorexia Nervosa in 74 participants. Enrolling by invitation.

Timeline

12 October 2021

Primary endpoint
3 June 2025

31 March 2026

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	ENROLLING BY INVITATION
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	74
Start date	12 October 2021
Primary completion	3 June 2025
Estimated completion	31 March 2026
Sites	2 locations across United States

Drugs / interventions tested

Individualized Caloric Refeeding (ICR)
Higher Calorie Refeeding (HCR)

Conditions studied

Atypical Anorexia Nervosa — all drugs for Atypical Anorexia Nervosa →

Sponsor

University of California, San Francisco

Who can join

Adults 12 to 24, any sex, with Atypical Anorexia Nervosa. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary purpose of the trial is to compare the efficacy and safety of Individualized Caloric Refeeding (ICR) to the new standard of care, Higher Calorie Refeeding (HCR), in hospitalized patients with atypical anorexia nervosa (AAN), and clinical remission over one year of follow-up.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Atypical Anorexia Nervosa

Currently open trials in the same condition.

NCT06624150 — tDCS and Cognitive Training for Restrictive Eating Disorders · Phase 1 · recruiting

Other University of California, San Francisco trials

Trials by the same sponsor.

NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04966858 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
Last refreshed: 23 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04966858.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing