NCT04960605

Prognosis of Dental Implants in Patients With Primary Sjögren's Syndrome

Completed NA Last updated 1 December 2023

What this trial tests

NA trial testing Dental implants in Dental Implant in 48 participants. Completed in 27 October 2023.

Timeline

1 January 2015

Primary endpoint
27 October 2023

27 October 2023

Quick facts

Lead sponsor	University of Copenhagen
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	48
Start date	1 January 2015
Primary completion	27 October 2023
Estimated completion	27 October 2023

Drugs / interventions tested

• Dental implants

Conditions studied

• Dental Implant — all drugs for Dental Implant →
• Primary Sjögren Syndrome — all drugs for Primary Sjögren Syndrome →

Sponsor

University of Copenhagen

Who can join

Adults 20 to 70, any sex, with Dental Implant or Primary Sjögren Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Primary Sjögren's Syndrome (PSS) is a chronic autoimmune inflammatory disease primarily involving the salivary and lacrimal glands. Few data exist regarding survival and success rate of dental implants in patients with PSS. Although a previous study suggest lower success rate for dental implants we hypothesize that dental implants have similar survival and success rate in PSS as healthy controls.

The purpose of the present study was to evaluate the long-term survival and success rate of dental implants in patients with PSS compared to the healthy controls.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Prognosis of Single Implant-Supported Prosthesis in Patients With Primary Sjögren's Syndrome: A Five-Year Prospective Clinical Study.
   Hosseini M, Jensen SS, Gotfredsen K, Hyldahl E, et al · · 2025 · cited 3× · PMID 39235273 · DOI 10.1111/clr.14356