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NCT04958187
An Open Label, Single-Dose Study to Evaluate the Safety and Pharmacokinetics of ANG-3777 Injected Intravenously in Stable Adult Maintenance Hemodialysis Subjects
Phase 1 trial testing ANG-3777 in Hemodialysis in 16 participants. Status unknown.
1 October 2021
Quick facts
| Lead sponsor | Angion Biomedica Corp |
|---|---|
| Phase | Phase 1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 16 |
| Start date | 1 July 2021 |
| Primary completion | 1 October 2021 |
| Estimated completion | 1 October 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- ANG-3777 — full drug profile →
Conditions studied
- Hemodialysis — all drugs for Hemodialysis →
Sponsor
Angion Biomedica Corp — full company profile →
Who can join
Adults 18 to 75, any sex, with Hemodialysis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Measure the pharmacokinetic (PK) parameters of a single dose of ANG-3777 including, but not limited to: Tmax
Time frame: Day 1 and Day 2 -
Measure the pharmacokinetic (PK) parameters of a single dose of ANG-3777 including, but not limited to: Cmax
Time frame: Day 1 and Day 2 -
Measure the pharmacokinetic (PK) parameters of a single dose of ANG-3777 including, but not limited to: AUC(0-last) and AUC(0-inf)
Time frame: Day 1 and Day 2
Sponsor's own description
The purpose of this study is to evaluate the pharmacokinetics and safety of a single-dose of ANG-3777 in subjects with renal failure receiving maintenance hemodialysis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04958187
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Angion Biomedica Corp trials
Trials by the same sponsor.
- NCT04939116 — Study of Safety and Efficacy of ANG-3070 in Chronic Kidney Disease · Phase 2 · unknown
- NCT04459676 — Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia · Phase 2 · unknown
- NCT04196179 — ANG-3070 in Healthy Adult Participants · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04958187 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Angion Biomedica Corp
- Last refreshed: 9 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04958187.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing