NCT04948385 is a Phase 4 clinical trial of Propofol in Driving Impaired, sponsored by University of Liege.

Who is sponsoring NCT04948385?

NCT04948385 is sponsored by University of Liege.

What drugs are being tested in NCT04948385?

Interventions in NCT04948385: Propofol, No sedation.

What condition does NCT04948385 study?

NCT04948385 studies Driving Impaired.

Is NCT04948385 still recruiting?

NCT04948385 is currently completed. Last updated 2 July 2021.

Last reviewed 2021-07-02 · How we verify

NCT04948385

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Driving Performance After Deep Sedation for Outpatient Endoscopy

Completed Phase 4 Last updated 2 July 2021

What this trial tests

Phase 4 trial testing Propofol in Driving Impaired in 60 participants. Completed in 6 May 2019.

Timeline

6 February 2019

Primary endpoint
6 May 2019

6 May 2019

Quick facts

Lead sponsor	University of Liege
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	60
Start date	6 February 2019
Primary completion	6 May 2019
Estimated completion	6 May 2019
Sites	1 location across Belgium

Drugs / interventions tested

Propofol (Propofol) — full drug profile →
No sedation — full drug profile →

Conditions studied

Driving Impaired — all drugs for Driving Impaired →

Sponsor

University of Liege

Who can join

18 and older, any sex, with Driving Impaired. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Many drugs used during anesthesia can reduce alertness and therefore present potential risks when driving a vehicle (risk of accident). Some scientific societies recommend not driving for 12 to 24 hours after sedation or general anesthesia. However, there are conflicting data in the literature showing that general anesthesia in healthy volunteers does not impair driving ability as early as 2 hours after the end of anesthesia. This need not to drive requires the outpatient to have an escort. Unfortunately, some patients find it difficult to benefit from an adult escort, which can lead to last minute cancellations, absences or the need for a classic overnight hospital stay. The main objective of the study is to compare with a simulator the driving performances of patients who have benefited from deep sedation for an outpatient endoscopic digestive procedure when they have met the discharge criteria to the performances of their escorts in order to determine if the conditions are as safe to let them drive home.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Propofol

Trials testing the same drug.

NCT07251101 — Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery · NA · not yet recruiting
NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
NCT07460050 — Comparison of Two Sedative Agents in Terms of Controlled Hypotension · NA · not yet recruiting
NCT07347496 — A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined · Phase 4 · not yet recruiting

Other recruiting trials for Driving Impaired

Currently open trials in the same condition.

NCT06872593 — Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal · NA · recruiting

Other University of Liege trials

Trials by the same sponsor.

NCT07523178 — Effects of a Targeted Prevention Program on Change-of-Direction Biomechanics and Performance in Elite Female Soccer Play · NA · not yet recruiting
NCT07472400 — Mobility, Strength, and Functional Outcomes Before Surgery, at 3 Months, and at 6 Months After Hip Arthroscopy for Femor · not yet recruiting
NCT07331779 — Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation · NA · not yet recruiting
NCT07237893 — Impact of a Physical Activity Intervention on Cardiometabolic Health, Mental Health, and Lifestyle Factors. · NA · not yet recruiting
NCT06964282 — Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthropl · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04948385 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Liege
Last refreshed: 2 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04948385.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing