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NCT04946760
Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease
NA trial testing Sham Manipulation in Parkinson Disease in 113 participants. Completed in 16 September 2019.
15 September 2019
Quick facts
| Lead sponsor | University of North Texas Health Science Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 113 |
| Start date | 1 September 2016 |
| Primary completion | 15 September 2019 |
| Estimated completion | 16 September 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Sham Manipulation
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
University of North Texas Health Science Center
Who can join
50 and older, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Parkinson Disease is a degenerative process that affects millions each year, and has devastating effects on patients and their families. The mobility symptoms that manifest as the disease progresses can result in social isolation as patients may be embarrassed or fear falling in public. One of the common risks resulting from the PD is falls. Falling in PD is primarily related to musculoskeletal issues such as muscular rigidity, postural instability \& stooped posture. These kinds of manifestations should be amenable to treatment with OMT. There are studies showing the positive impact that OMT has on gait in PD, and a study showing improvement in balance in non-PD subjects. This investigation is designed to address these components via the following specific aims: 1. Identify the effects of a Neck-down OMT (OMT-ND) protocol on gait kinematics and postural control in Parkinson disease The investigators hypothesize that the application of an OMT protocol will improve gait kinematics and increase subjects' ability to respond to a postural challenge. The theoretical mechanism for this is due to the improved joint flexibility, improved proprioception and decreased muscle co-activation. 2. Determine the efficacy of Whole-body OMT (OMT-WB) protocol including cranial manipulation on gait kinematics and postural control in Parkinson disease The investigators hypothesize that the addition of a cranial manipulation protocol will further improve gait kinematics and increase subjects' ability to respond to a postural challenge. The theoretical mechanism for this is due to the improved arterial blood flow to the brain, which results from improving the cranial bone motion, maximizing venous drainage, and reducing any restrictions around the vestibular system.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04946760
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Related trials
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Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
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- NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other University of North Texas Health Science Center trials
Trials by the same sponsor.
- NCT04978129 — Enhancing Quality in Protective Strategies · NA · completed
- NCT06025630 — Targeting Endoplasmic Reticulum Stress in Human Hypertension · Phase 1, PHASE2 · recruiting
- NCT05495087 — IHT for Mild Cognitive Impairment · NA · unknown
- NCT04333966 — Parental Research on Interventions for Social Media · NA · completed
- NCT05706181 — Heat Therapy, Functional Capacity, and Vascular Health in Older Adults · Phase 1, PHASE2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04946760 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of North Texas Health Science Center
- Last refreshed: 1 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04946760.
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