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NCT04944082

Remdesivir- Ivermectin Combination Therapy in Severe Covid-19

Status unknown Phase 4 Last updated 29 June 2021
What this trial tests

Phase 4 trial testing Ivermectin in Covid19 in 60 participants. Status unknown.

Timeline
1 July 2021
Primary endpoint
31 December 2021
31 December 2021

Quick facts

Lead sponsorAssiut University
PhasePhase 4
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment60
Start date1 July 2021
Primary completion31 December 2021
Estimated completion31 December 2021

Drugs / interventions tested

Conditions studied

Sponsor

Assiut University

Who can join

18 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Recent study reported in vitro synergistic interaction between two FDA approved drugs, remdesivir (RDV) and ivermectin (IVM) resulting in enhanced antiviral activity against SARS-CoV-2, the causative pathogen of COVID-19. The aim of the current study is comparing the efficacy and safety of combining remdesivir and ivermectin versus using remdesivir alone in patients with severe COVID-19.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment.
    Drożdżal S, Rosik J, Lechowicz K, Machaj F, et al · · 2021 · cited 186× · PMID 34991982 · DOI 10.1016/j.drup.2021.100794
  2. Ivermectin for preventing and treating COVID-19.
    Popp M, Reis S, Schießer S, Hausinger RI, et al · · 2022 · cited 30× · PMID 35726131 · DOI 10.1002/14651858.cd015017.pub3

Verify or expand the search:

Other trials of Ivermectin

Trials testing the same drug.

Other recruiting trials for Covid19

Currently open trials in the same condition.

Other Assiut University trials

Trials by the same sponsor.

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Data sources for this page

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